Synergistic activity of diclofenac sodium with oxacillin against planktonic cells and biofilm of methicillin-resistant <i>Staphylococcus aureus</i> strains.

Queiroz, Helaine A; da Silva, Cecília R; de Andrade Neto, João B; do Av Sá, Lívia G; do Nascimento, Francisca Bsa; Moreno, Leticia Ss; Barroso, Fátima Dd; da Silva, Lisandra J; Cândido, Thiago M; de Oliveira, Leilson C; de Mesquita, Jacó Rl; de Moraes, Manoel O; Cavalcanti, Bruno C; Nobre Júnior, Hélio V

Synergistic activity of diclofenac sodium with oxacillin against planktonic cells and biofilm of methicillin-resistant Staphylococcus aureus strains.

Queiroz, Helaine A; da Silva, Cecília R; de Andrade Neto, João B; do Av Sá, Lívia G; do Nascimento, Francisca Bsa; Moreno, Leticia Ss; Barroso, Fátima Dd; da Silva, Lisandra J; Cândido, Thiago M; de Oliveira, Leilson C; de Mesquita, Jacó Rl; de Moraes, Manoel O; Cavalcanti, Bruno C; Nobre Júnior, Hélio V.

Afiliação

Queiroz HA; Department of Clinical & Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
da Silva CR; Drug Research & Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
de Andrade Neto JB; Department of Clinical & Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
do Av Sá LG; Drug Research & Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
do Nascimento FB; Department of Clinical & Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Moreno LS; Drug Research & Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Barroso FD; University Center Christus, Fortaleza, CE, Brazil.
da Silva LJ; Department of Clinical & Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Cândido TM; Drug Research & Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
de Oliveira LC; University Center Christus, Fortaleza, CE, Brazil.
de Mesquita JR; Department of Clinical & Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
de Moraes MO; Drug Research & Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
Cavalcanti BC; Department of Clinical & Toxicological Analysis, School of Pharmacy, Laboratory of Bioprospection in Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
Nobre Júnior HV; Drug Research & Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.

Future Microbiol ; 16: 375-387, 2021 04.

Article em En | MEDLINE | ID: mdl-33870731

Assuntos

Antibacterianos/farmacologia; Biofilmes/efeitos dos fármacos; Diclofenaco/farmacologia; Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos; Oxacilina/farmacologia; Biofilmes/crescimento & desenvolvimento; Membrana Celular/efeitos dos fármacos; Dano ao DNA/efeitos dos fármacos; Sinergismo Farmacológico; Testes de Sensibilidade Microbiana

Palavras-chave

MRSA; apoptosis; biofilm; diclofenac sodium; flow cytometry; synergism

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxacilina / Diclofenaco / Biofilmes / Staphylococcus aureus Resistente à Meticilina / Antibacterianos Idioma: En Revista: Future Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil

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