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Randomized prospective evaluation of genome sequencing versus standard-of-care as a first molecular diagnostic test.
Brockman, Deanna G; Austin-Tse, Christina A; Pelletier, Renée C; Harley, Caroline; Patterson, Candace; Head, Holly; Leonard, Courtney Elizabeth; O'Brien, Kimberly; Mahanta, Lisa M; Lebo, Matthew S; Lu, Christine Y; Natarajan, Pradeep; Khera, Amit V; Aragam, Krishna G; Kathiresan, Sekar; Rehm, Heidi L; Udler, Miriam S.
Afiliação
  • Brockman DG; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. Deanna.brockman@mgh.harvard.edu.
  • Austin-Tse CA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA. Deanna.brockman@mgh.harvard.edu.
  • Pelletier RC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Harley C; Laboratory for Molecular Medicine, Partners Personalized Medicine, Cambridge, MA, USA.
  • Patterson C; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Head H; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Leonard CE; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • O'Brien K; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Mahanta LM; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • Lebo MS; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Lu CY; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Natarajan P; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • Khera AV; Laboratory for Molecular Medicine, Partners Personalized Medicine, Cambridge, MA, USA.
  • Aragam KG; Laboratory for Molecular Medicine, Partners Personalized Medicine, Cambridge, MA, USA.
  • Kathiresan S; Laboratory for Molecular Medicine, Partners Personalized Medicine, Cambridge, MA, USA.
  • Rehm HL; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
  • Udler MS; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
Genet Med ; 23(9): 1689-1696, 2021 09.
Article em En | MEDLINE | ID: mdl-33976420
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Genéticos / Patologia Molecular Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Child / Humans Idioma: En Revista: Genet Med Assunto da revista: GENETICA MEDICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Genéticos / Patologia Molecular Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Child / Humans Idioma: En Revista: Genet Med Assunto da revista: GENETICA MEDICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos