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Synthesis and biological evaluation of new 2-methoxyestradiol derivatives: Potent inhibitors of angiogenesis and tubulin polymerization.
Sun, Moran; Zhang, Yixin; Qin, Jinling; Ba, Mengyu; Yao, Yongfang; Duan, Yongtao; Liu, Hongmin; Yu, Dequan.
Afiliação
  • Sun M; School of Pharmaceutical Sciences, and Institute of Drug Discovery & Development, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China.
  • Zhang Y; School of Pharmaceutical Sciences, and Institute of Drug Discovery & Development, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China.
  • Qin J; School of Pharmaceutical Sciences, and Institute of Drug Discovery & Development, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China.
  • Ba M; School of Pharmaceutical Sciences, and Institute of Drug Discovery & Development, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China.
  • Yao Y; School of Pharmaceutical Sciences, and Institute of Drug Discovery & Development, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China. Electronic address: yongfangyao@zzu.edu.cn.
  • Duan Y; Henan Provincial Key Laboratory of Children's Genetics and Metabolic Diseases, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou 450018, China. Electronic address: duanyongtao860409@163.com.
  • Liu H; School of Pharmaceutical Sciences, and Institute of Drug Discovery & Development, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China. Electronic address: liuhm@zzu.edu.cn.
  • Yu D; Chinese Academy of Medical Sciences, Beijing 100021,China.
Bioorg Chem ; 113: 104988, 2021 08.
Article em En | MEDLINE | ID: mdl-34034135
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Inibidores da Angiogênese / Moduladores de Tubulina / 2-Metoxiestradiol / Neovascularização Patológica Limite: Animals / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Inibidores da Angiogênese / Moduladores de Tubulina / 2-Metoxiestradiol / Neovascularização Patológica Limite: Animals / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China