Interaction between CD9 and PI3K­p85 activates the PI3K/AKT signaling pathway in B­lineage acute lymphoblastic leukemia.

Shi, Yi-Fen; Huang, Zi-Yang; Huang, Yi-Sha; Dong, Ru-Jiao; Xing, Chong-Yun; Yu, Kang; Leung, Kam Tong; Feng, Jian-Hua

Interaction between CD9 and PI3Kp85 activates the PI3K/AKT signaling pathway in Blineage acute lymphoblastic leukemia.

Shi, Yi-Fen; Huang, Zi-Yang; Huang, Yi-Sha; Dong, Ru-Jiao; Xing, Chong-Yun; Yu, Kang; Leung, Kam Tong; Feng, Jian-Hua.

Afiliação

Shi YF; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Huang ZY; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Huang YS; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Dong RJ; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Xing CY; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Yu K; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Leung KT; Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR 999077, P.R. China.
Feng JH; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.

Oncol Rep ; 46(1)2021 07.

Article em En | MEDLINE | ID: mdl-34036396

Assuntos

Fosfatidilinositol 3-Quinases/metabolismo; Leucemia-Linfoma Linfoblástico de Células Precursoras B/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Tetraspanina 29/genética; Tetraspanina 29/metabolismo; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Cromonas/farmacologia; Progressão da Doença; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Técnicas de Silenciamento de Genes; Células HEK293; Humanos; Morfolinas/farmacologia; Fosforilação; Leucemia-Linfoma Linfoblástico de Células Precursoras B/genética; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Blineage acute lymphoblastic leukemia; CD9; PI3K/AKT signaling pathway; PI3Kp85; SUPB15 cells

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Tetraspanina 29 Limite: Humans Idioma: En Revista: Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google