Targeting the tetraspanin CD81 reduces cancer invasion and metastasis.

Vences-Catalán, Felipe; Rajapaksa, Ranjani; Kuo, Chiung-Chi; Miller, Caitlyn L; Lee, Anderson; Ramani, Vishnu C; Jeffrey, Stefanie S; Levy, Ronald; Levy, Shoshana

Vences-Catalán, Felipe; Rajapaksa, Ranjani; Kuo, Chiung-Chi; Miller, Caitlyn L; Lee, Anderson; Ramani, Vishnu C; Jeffrey, Stefanie S; Levy, Ronald; Levy, Shoshana.

Afiliação

Vences-Catalán F; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305.
Rajapaksa R; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305.
Kuo CC; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305.
Miller CL; Department of Bioengineering, Stanford University, Stanford, CA 94305.
Lee A; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305.
Ramani VC; Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305.
Jeffrey SS; Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305.
Levy R; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305; levy@stanford.edu slevy@stanford.edu.
Levy S; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305; levy@stanford.edu slevy@stanford.edu.

Proc Natl Acad Sci U S A ; 118(24)2021 06 15.

Article em En | MEDLINE | ID: mdl-34099563

Assuntos

Neoplasias da Mama/patologia; Tetraspanina 28/metabolismo; Animais; Anticorpos/farmacologia; Moléculas de Adesão Celular/metabolismo; Linhagem Celular Tumoral; Membrana Celular/efeitos dos fármacos; Membrana Celular/metabolismo; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Epitopos/metabolismo; Feminino; Humanos; Camundongos Endogâmicos BALB C; Camundongos Knockout; Camundongos SCID; Invasividade Neoplásica; Metástase Neoplásica; Receptores de Superfície Celular/metabolismo; Neoplasias de Mama Triplo Negativas/patologia; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

JAM-A; immunotherapy; xenograft

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Tetraspanina 28 Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article

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