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Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.
Chen, Zhi; Xiong, Liling; Jin, Huili; Yu, Jiaxiao; Li, Xin; Fu, Huijia; Wen, Li; Qi, Hongbo; Tong, Chao; Saffery, Richard; Kilby, Mark D; Baker, Philip N.
Afiliação
  • Chen Z; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Xiong L; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Jin H; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Yu J; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Li X; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Fu H; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Wen L; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Qi H; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Tong C; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Saffery R; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Kilby MD; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Baker PN; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Aging Cell ; 20(7): e13417, 2021 07.
Article em En | MEDLINE | ID: mdl-34105233

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Placenta / Trofoblastos / Proteínas Klotho Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Aging Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Placenta / Trofoblastos / Proteínas Klotho Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Aging Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China