Thermodynamic consequences of Tyr to Trp mutations in the cation-&#960;-mediated binding of trimethyllysine by the HP1 chromodomain.

Krone, Mackenzie W; Albanese, Katherine I; Leighton, Gage O; He, Cyndi Qixin; Lee, Ga Young; Garcia-Borràs, Marc; Guseman, Alex J; Williams, David C; Houk, K N; Brustad, Eric M; Waters, Marcey L

Thermodynamic consequences of Tyr to Trp mutations in the cation-π-mediated binding of trimethyllysine by the HP1 chromodomain.

Krone, Mackenzie W; Albanese, Katherine I; Leighton, Gage O; He, Cyndi Qixin; Lee, Ga Young; Garcia-Borràs, Marc; Guseman, Alex J; Williams, David C; Houk, K N; Brustad, Eric M; Waters, Marcey L.

Afiliação

Krone MW; University of North Carolina at Chapel Hill 131 South Road, Campus Box 3290 Chapel Hill NC 27599 USA mlwaters@email.unc.edu.
Albanese KI; University of North Carolina at Chapel Hill 131 South Road, Campus Box 3290 Chapel Hill NC 27599 USA mlwaters@email.unc.edu.
Leighton GO; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill 120 Mason Farm Rd, Campus Box 7260 Chapel Hill NC 27599 USA.
He CQ; Department of Chemistry and Biochemistry, University of California at Los Angeles 607 Charles E. Young Drive East, Box 951569 Los Angeles CA 90095-1569 USA.
Lee GY; Department of Chemistry and Biochemistry, University of California at Los Angeles 607 Charles E. Young Drive East, Box 951569 Los Angeles CA 90095-1569 USA.
Garcia-Borràs M; Department of Chemistry and Biochemistry, University of California at Los Angeles 607 Charles E. Young Drive East, Box 951569 Los Angeles CA 90095-1569 USA.
Guseman AJ; University of North Carolina at Chapel Hill 131 South Road, Campus Box 3290 Chapel Hill NC 27599 USA mlwaters@email.unc.edu.
Williams DC; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill Campus Box 7525, Brinkhous-Bullitt Building Chapel Hill NC 27599 USA.
Houk KN; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill 450 West Drive Chapel Hill NC 27599 USA.
Brustad EM; Department of Chemistry and Biochemistry, University of California at Los Angeles 607 Charles E. Young Drive East, Box 951569 Los Angeles CA 90095-1569 USA.
Waters ML; University of North Carolina at Chapel Hill 131 South Road, Campus Box 3290 Chapel Hill NC 27599 USA mlwaters@email.unc.edu.

Chem Sci ; 11(13): 3495-3500, 2020 Mar 04.

Article em En | MEDLINE | ID: mdl-34109021

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chem Sci Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chem Sci Ano de publicação: 2020 Tipo de documento: Article