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Synthesis, biological evaluation, and molecular docking analysis of novel linker-less benzamide based potent and selective HDAC3 inhibitors.
Routholla, Ganesh; Pulya, Sravani; Patel, Tarun; Abdul Amin, Sk; Adhikari, Nilanjan; Biswas, Swati; Jha, Tarun; Ghosh, Balaram.
Afiliação
  • Routholla G; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India.
  • Pulya S; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India.
  • Patel T; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India.
  • Abdul Amin S; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P. O. Box 17020, Jadavpur University, Kolkata 700032, West Bengal, India.
  • Adhikari N; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P. O. Box 17020, Jadavpur University, Kolkata 700032, West Bengal, India.
  • Biswas S; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India.
  • Jha T; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P. O. Box 17020, Jadavpur University, Kolkata 700032, West Bengal, India.
  • Ghosh B; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India. Electronic address: balaram@hyderabad.bits-pilani.ac.in.
Bioorg Chem ; 114: 105050, 2021 09.
Article em En | MEDLINE | ID: mdl-34120025
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Inibidores de Histona Desacetilases / Simulação de Acoplamento Molecular / Histona Desacetilases / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Inibidores de Histona Desacetilases / Simulação de Acoplamento Molecular / Histona Desacetilases / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia