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Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.
Lalazar, Gadi; Requena, David; Ramos-Espiritu, Lavoisier; Ng, Denise; Bhola, Patrick D; de Jong, Ype P; Wang, Ruisi; Narayan, Nicole J C; Shebl, Bassem; Levin, Solomon; Michailidis, Eleftherios; Kabbani, Mohammad; Vercauteren, Koen O A; Hurley, Arlene M; Farber, Benjamin A; Hammond, William J; Saltsman, James A; Weinberg, Ethan M; Glickman, J Fraser; Lyons, Barbara A; Ellison, Jessica; Schadde, Erik; Hertl, Martin; Leiting, Jennifer L; Truty, Mark J; Smoot, Rory L; Tierney, Faith; Kato, Tomoaki; Wendel, Hans-Guido; LaQuaglia, Michael P; Rice, Charles M; Letai, Anthony; Coffino, Philip; Torbenson, Michael S; Ortiz, Michael V; Simon, Sanford M.
Afiliação
  • Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Requena D; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.
  • Ramos-Espiritu L; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Ng D; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York.
  • Bhola PD; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • de Jong YP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Wang R; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.
  • Narayan NJC; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
  • Shebl B; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Levin S; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Michailidis E; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Kabbani M; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Vercauteren KOA; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Hurley AM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
  • Farber BA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
  • Hammond WJ; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
  • Saltsman JA; Laboratory of Liver Infectious Diseases, Ghent University, Ghent, Belgium.
  • Weinberg EM; Institute of Tropical Medicine, Antwerp, Belgium.
  • Glickman JF; Hospital Program Direction, The Rockefeller University, New York, New York.
  • Lyons BA; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Ellison J; Department of Surgery, Division of Pediatric Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
  • Schadde E; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Hertl M; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Leiting JL; Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York.
  • Truty MJ; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
  • Smoot RL; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Tierney F; Department of Surgery, Mount Sinai Hospital, New York, New York.
  • Kato T; Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Wendel HG; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York.
  • LaQuaglia MP; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico.
  • Rice CM; Division of Transplantation, Rush University Medical Center, Chicago, Illinois.
  • Letai A; Department of Surgery, Division of Transplantation and Division of Surgical Oncology, Rush University Medical Center, Chicago, Illinois.
  • Coffino P; Division of Transplantation, Rush University Medical Center, Chicago, Illinois.
  • Torbenson MS; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.
  • Ortiz MV; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.
  • Simon SM; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Cancer Discov ; 11(10): 2544-2563, 2021 10.
Article em En | MEDLINE | ID: mdl-34127480
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Carcinoma Hepatocelular / Ensaios Antitumorais Modelo de Xenoenxerto / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Discov Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Carcinoma Hepatocelular / Ensaios Antitumorais Modelo de Xenoenxerto / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Discov Ano de publicação: 2021 Tipo de documento: Article