Long-term survivors of murine sepsis are predisposed to enhanced LPS-induced lung injury and proinflammatory immune reprogramming.

Denstaedt, Scott J; Bustamante, Angela C; Newstead, Michael W; Moore, Bethany B; Standiford, Theodore J; Zemans, Rachel L; Singer, Benjamin H

Denstaedt, Scott J; Bustamante, Angela C; Newstead, Michael W; Moore, Bethany B; Standiford, Theodore J; Zemans, Rachel L; Singer, Benjamin H.

Afiliação

Denstaedt SJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Bustamante AC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Newstead MW; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Moore BB; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Standiford TJ; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan.
Zemans RL; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Singer BH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.

Am J Physiol Lung Cell Mol Physiol ; 321(2): L451-L465, 2021 08 01.

Article em En | MEDLINE | ID: mdl-34161747

Assuntos

Lipopolissacarídeos/toxicidade; Lesão Pulmonar/imunologia; Sepse/imunologia; Animais; Calgranulina A/imunologia; Calgranulina B/imunologia; Feminino; Humanos; Inflamação/induzido quimicamente; Inflamação/imunologia; Inflamação/patologia; Lesão Pulmonar/induzido quimicamente; Lesão Pulmonar/patologia; Masculino; Camundongos; Monócitos/imunologia; Monócitos/patologia; Sepse/induzido quimicamente; Sepse/patologia; Fator de Necrose Tumoral alfa/imunologia

Palavras-chave

lung injury; monocyte; priming; sepsis; sepsis survival

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Sepse / Lesão Pulmonar Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article

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