Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway.

Zhuo, Youqiong; Yuan, Renyikun; Chen, Xinxin; He, Jia; Chen, Yangling; Zhang, Chenwei; Sun, Kaili; Yang, Shilin; Liu, Zhenjie; Gao, Hongwei

Zhuo, Youqiong; Yuan, Renyikun; Chen, Xinxin; He, Jia; Chen, Yangling; Zhang, Chenwei; Sun, Kaili; Yang, Shilin; Liu, Zhenjie; Gao, Hongwei.

Afiliação

Zhuo Y; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Yuan R; Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development, Nanning, 530200, China.
Chen X; State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
He J; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Chen Y; Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development, Nanning, 530200, China.
Zhang C; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Sun K; Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development, Nanning, 530200, China.
Yang S; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Liu Z; Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development, Nanning, 530200, China.
Gao H; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.

Chin Med ; 16(1): 48, 2021 Jun 28.

Article em En | MEDLINE | ID: mdl-34183021

Palavras-chave

Akt/Nrf2; Myocardial ischemia reperfusion; Necroptosis; Oxidative stress; RIP1/RIP3/MLKL; Tanshinone I

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Chin Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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