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Molecular Interactions between Dietary Lipids and Bone Tissue during Aging.
Romero-Márquez, Jose M; Varela-López, Alfonso; Navarro-Hortal, María D; Badillo-Carrasco, Alberto; Forbes-Hernández, Tamara Y; Giampieri, Francesca; Domínguez, Irma; Madrigal, Lorena; Battino, Maurizio; Quiles, José L.
Afiliação
  • Romero-Márquez JM; Department of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.
  • Varela-López A; Department of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.
  • Navarro-Hortal MD; Department of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.
  • Badillo-Carrasco A; Department of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.
  • Forbes-Hernández TY; Nutrition and Food Science Group, Department of Analytical and Food Chemistry, CITACA, CACTI, University of Vigo, 36310 Vigo, Spain.
  • Giampieri F; Department of Clinical Sicences, Università Politecnica delle Marche, 60131 Ancona, Italy.
  • Domínguez I; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
  • Madrigal L; Research Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, Isabel Torres 21, 39011 Santander, Spain.
  • Battino M; Universidad Internacional Iberoamericana, Calle 15 Num. 36, Entre 10 y 12 IMI III, Campeche 24560, Mexico.
  • Quiles JL; Universidad Internacional Iberoamericana, Calle 15 Num. 36, Entre 10 y 12 IMI III, Campeche 24560, Mexico.
Int J Mol Sci ; 22(12)2021 Jun 17.
Article em En | MEDLINE | ID: mdl-34204176
Age-related bone disorders such as osteoporosis or osteoarthritis are a major public health problem due to the functional disability for millions of people worldwide. Furthermore, fractures are associated with a higher degree of morbidity and mortality in the long term, which generates greater financial and health costs. As the world population becomes older, the incidence of this type of disease increases and this effect seems notably greater in those countries that present a more westernized lifestyle. Thus, increased efforts are directed toward reducing risks that need to focus not only on the prevention of bone diseases, but also on the treatment of persons already afflicted. Evidence is accumulating that dietary lipids play an important role in bone health which results relevant to develop effective interventions for prevent bone diseases or alterations, especially in the elderly segment of the population. This review focuses on evidence about the effects of dietary lipids on bone health and describes possible mechanisms to explain how lipids act on bone metabolism during aging. Little work, however, has been accomplished in humans, so this is a challenge for future research.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osso e Ossos / Envelhecimento / Gorduras na Dieta Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osso e Ossos / Envelhecimento / Gorduras na Dieta Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha