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Infant T-cell acute lymphoblastic leukaemia with t(6;7) (TCRB-MYB) translocation.
Ramdeny, Pemantah Sandheeah; Mullanfroze, Khushnuma; de Lorenzo, Paola; Grazia Valsecchi, Maria; Meijerink, Jules; Pieters, Rob; Baruchel, Andre; Vora, Ajay.
Afiliação
  • Ramdeny PS; Department of Haematology, Great Ormond Street Hospital, London, UK.
  • Mullanfroze K; Department of Haematology, Great Ormond Street Hospital, London, UK.
  • de Lorenzo P; Center of Bioinformatics, Biostatistics and Bioimaging, University of Milano-Bicocca, Monza, Italy.
  • Grazia Valsecchi M; Pediatrics, School of Medicine and Surgery, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy.
  • Meijerink J; Center of Bioinformatics, Biostatistics and Bioimaging, University of Milano-Bicocca, Monza, Italy.
  • Pieters R; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Baruchel A; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Vora A; Université de Paris and Hôpital Universitaire Robert Debré(APHP), Paris, France.
Br J Haematol ; 194(3): 613-616, 2021 08.
Article em En | MEDLINE | ID: mdl-34212378
T-ALL is rare in infancy with only 10 (1.5%) of 651 patients of that subtype in the Interfant-06 infant ALL trial. We report 3 cases of t(6;7) (TCR/MYB) infant T-cell Acute Lymphoblastic Leukaemia who appear to have a distinct clinical presentation with CNS disease and refractory disease or late relapse.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T alfa-beta / Proteínas Proto-Oncogênicas c-myb / Leucemia-Linfoma Linfoblástico de Células T Precursoras Limite: Humans / Infant Idioma: En Revista: Br J Haematol Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T alfa-beta / Proteínas Proto-Oncogênicas c-myb / Leucemia-Linfoma Linfoblástico de Células T Precursoras Limite: Humans / Infant Idioma: En Revista: Br J Haematol Ano de publicação: 2021 Tipo de documento: Article