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Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis.
Shankar-Hari, Manu; Vale, Claire L; Godolphin, Peter J; Fisher, David; Higgins, Julian P T; Spiga, Francesca; Savovic, Jelena; Tierney, Jayne; Baron, Gabriel; Benbenishty, Julie S; Berry, Lindsay R; Broman, Niklas; Cavalcanti, Alexandre Biasi; Colman, Roos; De Buyser, Stefanie L; Derde, Lennie P G; Domingo, Pere; Omar, Sharifah Faridah; Fernandez-Cruz, Ana; Feuth, Thijs; Garcia, Felipe; Garcia-Vicuna, Rosario; Gonzalez-Alvaro, Isidoro; Gordon, Anthony C; Haynes, Richard; Hermine, Olivier; Horby, Peter W; Horick, Nora K; Kumar, Kuldeep; Lambrecht, Bart N; Landray, Martin J; Leal, Lorna; Lederer, David J; Lorenzi, Elizabeth; Mariette, Xavier; Merchante, Nicolas; Misnan, Nor Arisah; Mohan, Shalini V; Nivens, Michael C; Oksi, Jarmo; Perez-Molina, Jose A; Pizov, Reuven; Porcher, Raphael; Postma, Simone; Rajasuriar, Reena; Ramanan, Athimalaipet V; Ravaud, Philippe; Reid, Pankti D; Rutgers, Abraham; Sancho-Lopez, Aranzazu.
Afiliação
  • Shankar-Hari M; Guy's and St Thomas' NHS Foundation Trust, ICU Support Offices, St Thomas' Hospital, London, England.
  • Vale CL; School of Immunology and Microbial Sciences, Kings College London, London, England.
  • Godolphin PJ; University College London, MRC Clinical Trials Unit at UCL, London, England.
  • Fisher D; University College London, MRC Clinical Trials Unit at UCL, London, England.
  • Higgins JPT; University College London, MRC Clinical Trials Unit at UCL, London, England.
  • Spiga F; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England.
  • Savovic J; NIHR Bristol Biomedical Research Centre, Bristol, England.
  • Tierney J; National Institute for Health Research Applied Research Collaboration West at University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, England.
  • Baron G; University of Bristol, Bristol, England.
  • Benbenishty JS; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England.
  • Berry LR; National Institute for Health Research Applied Research Collaboration West at University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, England.
  • Broman N; University College London, MRC Clinical Trials Unit at UCL, London, England.
  • Cavalcanti AB; Assistance Publique-Hôpitaux de Paris, Centre for Clinical Epidemiology, Hôpital Hôtel-Dieu, Paris, France.
  • Colman R; INSERM UMRS-1153, Centre de Recherche Epidémiologie et Statistique Université de Paris, METHODS Team, Paris, France.
  • De Buyser SL; Department of Nursing, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
  • Derde LPG; Berry Consultants, Austin, Texas.
  • Domingo P; Turku University Hospital, Department of Infectious Diseases, Turku, Finland.
  • Omar SF; BP-A Beneficência Portuguesa de São Paulo, Rua Maestro Cardim, São Paulo, Brazil.
  • Fernandez-Cruz A; Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.
  • Feuth T; Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.
  • Garcia F; Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Garcia-Vicuna R; Department of Infectious Diseases, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Gonzalez-Alvaro I; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
  • Gordon AC; Infectious Diseases Unit, Internal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.
  • Haynes R; Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland.
  • Hermine O; Infectious Diseases Department, Hospital Clinic Barcelona-IDIBAPS, Barcelona, Spain.
  • Horby PW; Rheumatology, Hospital Universitario La Princesa IIS-IP, Madrid, Spain.
  • Horick NK; Rheumatology, Hospital Universitario La Princesa IIS-IP, Madrid, Spain.
  • Kumar K; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, England.
  • Lambrecht BN; Nuffield Department of Population Health, University of Oxford, Oxford, England.
  • Landray MJ; MRC Population Health Research Unit, University of Oxford, Oxford, England.
  • Leal L; Department of Hematology, Necker Hospital, Paris, France.
  • Lederer DJ; Imagine Institute, University of Paris, INSERM U1153, Paris, France.
  • Lorenzi E; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, England.
  • Mariette X; International Severe Acute Respiratory and Emerging Infections Consortium, University of Oxford, Oxford, England.
  • Merchante N; Pandemic Sciences Centre, University of Oxford, Oxford, England.
  • Misnan NA; Department of Medicine, Massachusetts General Hospital, Boston.
  • Mohan SV; Medanta-The Medicity, Institute of Liver Transplantation and Regenerative Medicine, Gurugram, India.
  • Nivens MC; Research Department, Medanta Institute of Education and Research, Gurugram, India.
  • Oksi J; VIB Center for Inflammation Research, Ghent University, Ghent, Belgium.
  • Perez-Molina JA; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Pizov R; Nuffield Department of Population Health, University of Oxford, Oxford, England.
  • Porcher R; MRC Population Health Research Unit, University of Oxford, Oxford, England.
  • Postma S; Infectious Diseases Department, Hospital Clinic Barcelona-IDIBAPS, Barcelona, Spain.
  • Rajasuriar R; Regeneron Pharmaceuticals Inc, Tarrytown, New York.
  • Ramanan AV; Berry Consultants, Austin, Texas.
  • Ravaud P; Centre for Immunology of Viral Infections and Autoimmune Diseases, Université Paris-Saclay, INSERM UMR1184, Le Kremlin-Bicêtre, Paris, France.
  • Reid PD; Department of Rheumatology, Assistance Publique-Hôpitaux de Paris, Le Le Kremlin-Bicêtre, Paris, France.
  • Rutgers A; Unit of Infectious Diseases and Microbiology, Valme University Hospital, Institute of Biomedicine of Sevilla, Seville, Spain.
  • Sancho-Lopez A; Hospital Sungai Buloh, Ministry of Health, Buloh, Malaysia.
JAMA ; 326(6): 499-518, 2021 08 10.
Article em En | MEDLINE | ID: mdl-34228774
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interleucina-6 / Anticorpos Monoclonais Humanizados / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interleucina-6 / Anticorpos Monoclonais Humanizados / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido