Pituitary corticotroph tumour with adrenocortical cells: A distinct clinicopathologic entity with unique morphology and methylation profile.
Neuropathol Appl Neurobiol
; 48(2): e12754, 2022 02.
Article
em En
| MEDLINE
| ID: mdl-34296770
ABSTRACT
We describe a rare TPIT-positive corticotroph PitNET that is admixed with SF1-positive adrenocortical cells. This dimorphous population of cells showed no colocalisation between TPIT and SF1 by immunofluorescence, and an adrenocortical choristoma was favoured. Methylation array analysis revealed a novel methylation profile in relation to other pituitary neoplasms.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hipófise
/
Neoplasias Hipofisárias
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Metilação de DNA
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Adenoma Hipofisário Secretor de ACT
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Corticotrofos
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Neuropathol Appl Neurobiol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos