Generation of three iPSC lines from different types of pediatric acute leukemia patients.
Stem Cell Res
; 55: 102460, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-34298433
ABSTRACT
Leukemia is the most common malignant tumor in childhood. The pathogenesis of leukemia is still unclear. Therefore, it is imperative to establish effective disease models. In our study, we reprogrammed different types of pediatric acute leukemia cells into iPSCs using CytoTune®Sendai virus. All generated iPSCs maintained pluripotency and spontaneous in vivo differentiation capacity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Leucemia Mieloide Aguda
/
Células-Tronco Pluripotentes Induzidas
Limite:
Child
/
Humans
Idioma:
En
Revista:
Stem Cell Res
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China