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A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China.
Guo, Chengxian; Hu, Biwen; Guo, Chengjun; Meng, Xiangguang; Kuang, Yun; Huang, Longjian; Wang, Danling; Xu, Kangwei; Zhao, Yanlin; Yang, Guoping; Cai, Weimin; Shu, Yan.
Afiliação
  • Guo C; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
  • Hu B; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
  • Guo C; School of Applied Mathematics, Guangdong University of Technology, Guangzhou, China.
  • Meng X; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, China.
  • Kuang Y; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
  • Huang L; Youjiang Medical University for Nationalities, Baise, China.
  • Wang D; Department of Neuroscience, Hengyang School of Medicine, University of South China, Hengyang, China.
  • Xu K; Changsha Central Hospital, University of South China, Hengyang, China.
  • Zhao Y; Hunan Normal University School of Medicine, Changsha, China.
  • Yang G; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
  • Cai W; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
  • Shu Y; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China.
Front Pharmacol ; 12: 682020, 2021.
Article em En | MEDLINE | ID: mdl-34322018
To elucidate current domestic factors influencing pharmacogenomics (PGx) implementation and its future in China, we conducted a questionnaire survey on PGx applications and testing. A questionnaire-based survey was created on the popular online professional survey platform "Wenjuanxing" (www.wjx.cn) and performed via the social media platform WeChat. Among 422 participants, there were physicians (27.7%), pharmacists (31.3%), and researchers (41.0%). We found that less than 50% of physicians were aware of the importance of PGx in drug therapy, while over 50% of pharmacists and researchers recognized the importance. Only 38.5% of physicians, 40.9% of pharmacists, and 55.5% of researchers concurred that PGx analysis could lower the economic burdens for patients. However, most of the responders affirmed that PGx should be effectively implemented in clinical practices. A lack of sector standards, a lack of clinical research, and a lack of guidelines were found to be the major factors for hindering PGx clinical application. Among drugs associated with PGx assays, the most common were warfarin and clopidogrel. Although PGx research has advanced rapidly in recent years in mainland China, the clinical implementation of PGx has a long way to go.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Qualitative_research Idioma: En Revista: Front Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Qualitative_research Idioma: En Revista: Front Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China