Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats.

Abdulkareem Aljumaily, Sara Asaad; Demir, Mehmet; Elbe, Hulya; Yigitturk, Gurkan; Bicer, Yasemin; Altinoz, Eyup

Abdulkareem Aljumaily, Sara Asaad; Demir, Mehmet; Elbe, Hulya; Yigitturk, Gurkan; Bicer, Yasemin; Altinoz, Eyup.

Afiliação

Abdulkareem Aljumaily SA; Department of Medical Biochemistry, Faculty of Medicine, Karabuk University, Karabuk, Turkey.
Demir M; Department of Physiology, Faculty of Medicine, Karabuk University, Karabuk, Turkey.
Elbe H; Department of Histology and Embryology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Yigitturk G; Department of Histology and Embryology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Bicer Y; Department of Medical Biochemistry, Faculty of Medicine, Karabuk University, Karabuk, Turkey.
Altinoz E; Department of Medical Biochemistry, Faculty of Medicine, Karabuk University, Karabuk, Turkey. eyupaltinoz@karabuk.edu.tr.

Environ Sci Pollut Res Int ; 28(46): 65802-65813, 2021 Dec.

Article em En | MEDLINE | ID: mdl-34322808

Assuntos

Antioxidantes; Doxorrubicina; Animais; Anti-Inflamatórios/farmacologia; Antioxidantes/metabolismo; Cardiotoxicidade/tratamento farmacológico; Cardiotoxicidade/metabolismo; Carotenoides; Humanos; Miocárdio/metabolismo; Estresse Oxidativo; Ratos

Palavras-chave

Doxorubicin; apoptosis; crocin; myocardial toxicity; oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doxorrubicina / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Environ Sci Pollut Res Int Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Turquia

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