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Clinical evaluation of the potential drug-drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam.
Ren, Song; Vishwanathan, Karthick; Cantarini, Mireille; Frewer, Paul; Hara, Indira; Scarfe, Graeme; Burke, Wendy; Schalkwijk, Stein; Li, Yan; Han, David; Goldwater, Ronald.
Afiliação
  • Ren S; Clinical Pharmacology & Quantitative Pharmacology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Vishwanathan K; Clinical Pharmacology & Quantitative Pharmacology, CPSS, R&D, AstraZeneca, Boston, Massachusetts, USA.
  • Cantarini M; Oncology Late Development, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Frewer P; Oncology Biometrics, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Hara I; Patient Safety, Oncology TA, MedImmune-AstraZeneca, Cambridge, UK.
  • Scarfe G; Drug Metabolism and Pharmacokinetics, Oncology R&D, Research & Early Development, AstraZeneca, Cambridge, UK.
  • Burke W; Covance Clinical Research Unit, Leeds, UK.
  • Schalkwijk S; Clinical Pharmacology & Quantitative Pharmacology, CPSS, R&D, AstraZeneca, Cambridge, UK.
  • Li Y; Integrated Bioanalysis, Clinical Pharmacology & Quantitative Pharmacology, BioPharmaceuticals R&D, AstraZeneca, Boston, Massachusetts, USA.
  • Han D; Parexel International, Glendale, California, USA.
  • Goldwater R; Parexel International, Baltimore, Maryland, USA.
Br J Clin Pharmacol ; 88(2): 655-668, 2022 02.
Article em En | MEDLINE | ID: mdl-34322894
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Midazolam / Itraconazol Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Br J Clin Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Midazolam / Itraconazol Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Br J Clin Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos