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Inhibition of elastase enhances the adjuvanticity of alum and promotes anti-SARS-CoV-2 systemic and mucosal immunity.
Kim, Eunsoo; Attia, Zayed; Woodfint, Rachel M; Zeng, Cong; Kim, Sun Hee; Steiner, Haley E; Shukla, Rajni Kant; Liyanage, Namal P M; Ghimire, Shristi; Li, Jianrong; Renukaradhya, Gourapura J; Satoskar, Abhay R; Amer, Amal O; Liu, Shan-Lu; Cormet-Boyaka, Estelle; Boyaka, Prosper N.
Afiliação
  • Kim E; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Attia Z; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Woodfint RM; Department of Medicine and Infectious Diseases, University of Sadat City, 32897 Sadat City, Egypt.
  • Zeng C; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Kim SH; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Steiner HE; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Shukla RK; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Liyanage NPM; Department of Microbial Immunity and Infection, The Ohio State University, Columbus, OH 43210.
  • Ghimire S; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Li J; Department of Microbial Immunity and Infection, The Ohio State University, Columbus, OH 43210.
  • Renukaradhya GJ; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.
  • Satoskar AR; Food Animal Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691.
  • Amer AO; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Liu SL; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.
  • Cormet-Boyaka E; Food Animal Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691.
  • Boyaka PN; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.
Proc Natl Acad Sci U S A ; 118(34)2021 08 24.
Article em En | MEDLINE | ID: mdl-34353890

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adjuvantes Imunológicos / Elastase de Leucócito / Inibidores Enzimáticos / Compostos de Alúmen / SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adjuvantes Imunológicos / Elastase de Leucócito / Inibidores Enzimáticos / Compostos de Alúmen / SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article