Mesenchymal stem cells and local tacrolimus delivery synergistically enhance neurite extension.

Saffari, Sara; Saffari, Tiam M; Chan, Katelyn; Borschel, Gregory H; Shin, Alexander Y

Saffari, Sara; Saffari, Tiam M; Chan, Katelyn; Borschel, Gregory H; Shin, Alexander Y.

Afiliação

Saffari S; Division of Hand and Microvascular Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Saffari TM; Department of Plastic-, Reconstructive- and Hand Surgery, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Chan K; Division of Hand and Microvascular Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Borschel GH; Department of Plastic-, Reconstructive- and Hand Surgery, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Shin AY; Division of Plastic and Reconstructive Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.

Biotechnol Bioeng ; 118(11): 4477-4487, 2021 11.

Article em En | MEDLINE | ID: mdl-34396506

Assuntos

Gânglios Espinais/metabolismo; Transplante de Células-Tronco Mesenquimais; Células-Tronco Mesenquimais/metabolismo; Regeneração Nervosa/efeitos dos fármacos; Neuritos/metabolismo; Tacrolimo/farmacologia; Aloenxertos; Animais; Ratos; Ratos Endogâmicos Lew; Ratos Sprague-Dawley

Palavras-chave

local drug delivery; mesenchymal stem cells; nerve regeneration; peripheral nerve injury; tacrolimus (FK506)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuritos / Tacrolimo / Transplante de Células-Tronco Mesenquimais / Células-Tronco Mesenquimais / Gânglios Espinais / Regeneração Nervosa Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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