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Treatment with ROS detoxifying gold quantum clusters alleviates the functional decline in a mouse model of Friedreich ataxia.
Villa, Chiara; Legato, Mariella; Umbach, Alessandro; Riganti, Chiara; Jones, Rebecca; Martini, Beatrice; Boido, Marina; Medana, Claudio; Facchinetti, Irene; Barni, Dario; Pinto, Milena; Arguello, Tania; Belicchi, Marzia; Fagiolari, Gigliola; Liaci, Carla; Moggio, Maurizio; Ruffo, Riccardo; Moraes, Carlos T; Monguzzi, Angelo; Merlo, Giorgio R; Torrente, Yvan.
Afiliação
  • Villa C; Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Centro Dino Ferrari, Via F. Sforza 35, 20122 Milano, Italy.
  • Legato M; Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Centro Dino Ferrari, Via F. Sforza 35, 20122 Milano, Italy.
  • Umbach A; Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza, 52 10126 Torino, Italy.
  • Riganti C; Department of Oncology, University of Turin, Via Santena 5/bis, 10126 Torino, Italy.
  • Jones R; Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza, 52 10126 Torino, Italy.
  • Martini B; Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Centro Dino Ferrari, Via F. Sforza 35, 20122 Milano, Italy.
  • Boido M; Department of Neuroscience "Rita Levi Montalcini", Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Regione Gonzole 10, Orbassano,10043 Torino, Italy.
  • Medana C; Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza, 52 10126 Torino, Italy.
  • Facchinetti I; Department of Material Science, University of Milano Bicocca, Via R. Cozzi 55, 20125 Milano, Italy.
  • Barni D; Department of Material Science, University of Milano Bicocca, Via R. Cozzi 55, 20125 Milano, Italy.
  • Pinto M; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Arguello T; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Belicchi M; Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Centro Dino Ferrari, Via F. Sforza 35, 20122 Milano, Italy.
  • Fagiolari G; Neuromuscular and Rare Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122 Milan, Italy.
  • Liaci C; Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza, 52 10126 Torino, Italy.
  • Moggio M; Neuromuscular and Rare Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122 Milan, Italy.
  • Ruffo R; Department of Material Science, University of Milano Bicocca, Via R. Cozzi 55, 20125 Milano, Italy.
  • Moraes CT; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Monguzzi A; Department of Material Science, University of Milano Bicocca, Via R. Cozzi 55, 20125 Milano, Italy.
  • Merlo GR; Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza, 52 10126 Torino, Italy.
  • Torrente Y; Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Centro Dino Ferrari, Via F. Sforza 35, 20122 Milano, Italy. yvan.torrente@unimi.it.
Sci Transl Med ; 13(607)2021 08 18.
Article em En | MEDLINE | ID: mdl-34408077
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataxia de Friedreich Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataxia de Friedreich Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália