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Microglial activation and tau propagate jointly across Braak stages.
Pascoal, Tharick A; Benedet, Andrea L; Ashton, Nicholas J; Kang, Min Su; Therriault, Joseph; Chamoun, Mira; Savard, Melissa; Lussier, Firoza Z; Tissot, Cécile; Karikari, Thomas K; Ottoy, Julie; Mathotaarachchi, Sulantha; Stevenson, Jenna; Massarweh, Gassan; Schöll, Michael; de Leon, Mony J; Soucy, Jean-Paul; Edison, Paul; Blennow, Kaj; Zetterberg, Henrik; Gauthier, Serge; Rosa-Neto, Pedro.
Afiliação
  • Pascoal TA; Departments of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. PASCOAL@pitt.edu.
  • Benedet AL; Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. PASCOAL@pitt.edu.
  • Ashton NJ; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Kang MS; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada. PASCOAL@pitt.edu.
  • Therriault J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Chamoun M; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Savard M; Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Institute Clinical Neuroscience Institute, King's College London, London, UK.
  • Lussier FZ; NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley, NHS Foundation, London, UK.
  • Tissot C; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Karikari TK; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Ottoy J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Mathotaarachchi S; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Stevenson J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Massarweh G; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Schöll M; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • de Leon MJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Soucy JP; Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
  • Edison P; LC Campbell Cognitive Neurology Unit, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
  • Blennow K; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Zetterberg H; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, and Departments of Neurology, Neuros
  • Gauthier S; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Rosa-Neto P; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Nat Med ; 27(9): 1592-1599, 2021 09.
Article em En | MEDLINE | ID: mdl-34446931
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Peptídeos beta-Amiloides / Proteínas tau / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Peptídeos beta-Amiloides / Proteínas tau / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos