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Antisense inhibition of the Escherichia coli NrdAB aerobic ribonucleotide reductase is bactericidal due to induction of DNA strand breaks.
Campion, Christopher; Charbon, Godefroid; Thomsen, Thomas T; Nielsen, Peter E; Løbner-Olesen, Anders.
Afiliação
  • Campion C; Department of Cellular and Molecular Medicine, Faculty of Health Sciences, Center for Peptide-Based Antibiotics, The Panum Institute, University of Copenhagen, Blegdamsvej 3c, 2200 Copenhagen N, Denmark.
  • Charbon G; Department of Biology, Faculty of Science, Section for Functional Genomics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.
  • Thomsen TT; Department of Biology, Faculty of Science, Section for Functional Genomics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.
  • Nielsen PE; Department of Biology, Faculty of Science, Section for Functional Genomics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.
  • Løbner-Olesen A; Department of Clinical Microbiology, Rigshospitalet, Henrik Harpestreng Vej 4A, 2100 Copenhagen, Denmark.
J Antimicrob Chemother ; 76(11): 2802-2814, 2021 10 11.
Article em En | MEDLINE | ID: mdl-34450639
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonucleotídeo Redutases / Ácidos Nucleicos Peptídicos Idioma: En Revista: J Antimicrob Chemother Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonucleotídeo Redutases / Ácidos Nucleicos Peptídicos Idioma: En Revista: J Antimicrob Chemother Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca