Congenital Cytomegalovirus Infection: Epidemiology, Timely Diagnosis, and Management.
Neoreviews
; 22(9): e606-e613, 2021 09.
Article
em En
| MEDLINE
| ID: mdl-34470762
ABSTRACT
Congenital cytomegalovirus (cCMV) infection is common because of the ubiquitous nature of the virus and the lack of an effective prevention strategy during pregnancy. Most infants with cCMV are asymptomatic, although a notable subset can have sequelae including, most commonly, sensorineural hearing loss and neurodevelopmental disability, which may not be present at birth. Timely screening for cytomegalovirus in the first weeks after birth is critical to appropriately diagnose congenital infection, evaluate affected infants, and determine the treatment course. Antiviral therapy with valganciclovir can optimize end hearing and neurodevelopmental outcomes in symptomatic infants. This review discusses the epidemiology and clinical manifestations of cCMV, targeted and universal screening approaches, and treatment and monitoring of infants with cCMV.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Citomegalovirus
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Doenças Fetais
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Perda Auditiva Neurossensorial
Tipo de estudo:
Diagnostic_studies
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Screening_studies
Limite:
Female
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Humans
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Infant
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Newborn
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Pregnancy
Idioma:
En
Revista:
Neoreviews
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Israel