Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions.

Tromp, Alisha; Robinson, Kate; Hall, Thomas E; Mowry, Bryan; Giacomotto, Jean

Tromp, Alisha; Robinson, Kate; Hall, Thomas E; Mowry, Bryan; Giacomotto, Jean.

Afiliação

Tromp A; Queensland Brain Institute, The University of Queensland, St Lucia, Queensland 4072, Australia.
Robinson K; Queensland Brain Institute, The University of Queensland, St Lucia, Queensland 4072, Australia.
Hall TE; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland 4072, Australia.
Mowry B; Queensland Brain Institute, The University of Queensland, St Lucia, Queensland 4072, Australia.
Giacomotto J; Queensland Centre for Mental Health Research, West Moreton Hospital and Health Service, Wacol, QLD 4076 Australia.

G3 (Bethesda) ; 11(12)2021 12 08.

Article em En | MEDLINE | ID: mdl-34499171

Assuntos

Sistemas CRISPR-Cas; Peixe-Zebra; Animais; Éxons; Genômica; RNA Guia de Cinetoplastídeos/genética; Peixe-Zebra/genética

Palavras-chave

CRISPR; deletion; genetic compensation; genomic region; guidelines; heteroduplex; indel; large; non-coding; zebrafish

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peixe-Zebra / Sistemas CRISPR-Cas Limite: Animals Idioma: En Revista: G3 (Bethesda) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália

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