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Hypoxia and TLR9 activation drive CXCL4 production in systemic sclerosis plasmacytoid dendritic cells via mtROS and HIF-2α.
Ottria, Andrea; Zimmermann, Maili; Paardekooper, Laurent M; Carvalheiro, Tiago; Vazirpanah, Nadia; Silva-Cardoso, Sandra; Affandi, Alsya J; Chouri, Eleni; V D Kroef, Maarten; Tieland, Ralph G; Bekker, Cornelis P J; Wichers, Catharina G K; Rossato, Marzia; Mocholi-Gimeno, Enric; Tekstra, Janneke; Ton, Evelien; van Laar, Jaap M; Cossu, Marta; Beretta, Lorenzo; Garcia Perez, Samuel; Pandit, Aridaman; Bonte-Mineur, Femke; Reedquist, Kris A; van den Bogaart, Geert; Radstake, Timothy R D J; Marut, Wioleta.
Afiliação
  • Ottria A; Laboratory of Translational Immunology.
  • Zimmermann M; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Paardekooper LM; Laboratory of Translational Immunology.
  • Carvalheiro T; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Vazirpanah N; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Silva-Cardoso S; Laboratory of Translational Immunology.
  • Affandi AJ; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Chouri E; Laboratory of Translational Immunology.
  • V D Kroef M; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Tieland RG; Laboratory of Translational Immunology.
  • Bekker CPJ; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Wichers CGK; Laboratory of Translational Immunology.
  • Rossato M; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Mocholi-Gimeno E; Laboratory of Translational Immunology.
  • Tekstra J; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Ton E; Laboratory of Translational Immunology.
  • van Laar JM; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Cossu M; Laboratory of Translational Immunology.
  • Beretta L; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Garcia Perez S; Laboratory of Translational Immunology.
  • Pandit A; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Bonte-Mineur F; Laboratory of Translational Immunology.
  • Reedquist KA; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • van den Bogaart G; Laboratory of Translational Immunology.
  • Radstake TRDJ; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht.
  • Marut W; Laboratory of Translational Immunology.
Rheumatology (Oxford) ; 61(6): 2682-2693, 2022 05 30.
Article em En | MEDLINE | ID: mdl-34559222
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico / Fator Plaquetário 4 / Espécies Reativas de Oxigênio / Receptor Toll-Like 9 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico / Fator Plaquetário 4 / Espécies Reativas de Oxigênio / Receptor Toll-Like 9 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article