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Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells.
Benvenuto, Monica; Ciuffa, Sara; Focaccetti, Chiara; Sbardella, Diego; Fazi, Sara; Scimeca, Manuel; Tundo, Grazia Raffaella; Barillari, Giovanni; Segni, Maria; Bonanno, Elena; Manzari, Vittorio; Modesti, Andrea; Masuelli, Laura; Coletta, Massimo; Bei, Roberto.
Afiliação
  • Benvenuto M; Saint Camillus International, University of Health and Medical Sciences, Via di Sant'Alessandro 8, 00131, Rome, Italy.
  • Ciuffa S; Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.
  • Focaccetti C; Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.
  • Sbardella D; Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.
  • Fazi S; Department of Human Science and Promotion of the Quality of Life, San Raffaele University Rome, Via di Val Cannuta 247, 00166, Rome, Italy.
  • Scimeca M; IRCCS-Fondazione Bietti, Rome, Italy.
  • Tundo GR; Department of Experimental Medicine, University of Rome "Sapienza", Viale Regina Elena 324, 00161, Rome, Italy.
  • Barillari G; Saint Camillus International, University of Health and Medical Sciences, Via di Sant'Alessandro 8, 00131, Rome, Italy.
  • Segni M; Department of Human Science and Promotion of the Quality of Life, San Raffaele University Rome, Via di Val Cannuta 247, 00166, Rome, Italy.
  • Bonanno E; Department of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.
  • Manzari V; IRCCS-Fondazione Bietti, Rome, Italy.
  • Modesti A; Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.
  • Masuelli L; Department of Maternal Infantile and Urological Sciences, University of Rome "Sapienza", Viale Regina Elena 324, 00161, Rome, Italy.
  • Coletta M; Pediatric Endocrinology Unit, Policlinico Umberto I, Viale Regina Elena 364, 00161, Rome, Italy.
  • Bei R; Saint Camillus International, University of Health and Medical Sciences, Via di Sant'Alessandro 8, 00131, Rome, Italy.
Sci Rep ; 11(1): 19051, 2021 09 24.
Article em En | MEDLINE | ID: mdl-34561494
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteases / Linfócitos do Interstício Tumoral / Complexo de Endopeptidases do Proteassoma / Proliferação de Células / Bortezomib / Neoplasias de Cabeça e Pescoço / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteases / Linfócitos do Interstício Tumoral / Complexo de Endopeptidases do Proteassoma / Proliferação de Células / Bortezomib / Neoplasias de Cabeça e Pescoço / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália