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[Four new lanostane triterpenoids from latex of Euphorbia resinifera].
Li, Miao-Miao; Qi, Yan-Ru; Feng, Ya-Ping; Liu, Wei; Yuan, Tao.
Afiliação
  • Li MM; College of Life Science, Jiangxi Normal University Nanchang 330022, China.
  • Qi YR; College of Life Science, Jiangxi Normal University Nanchang 330022, China.
  • Feng YP; College of Life Science, Jiangxi Normal University Nanchang 330022, China Key Lab of Natural Product Chemistry and Application at Universities of Education Department of Xinjiang Uygur Autonomous Region, Yili Normal University Yining 835000, China.
  • Liu W; Key Lab of Natural Product Chemistry and Application at Universities of Education Department of Xinjiang Uygur Autonomous Region, Yili Normal University Yining 835000, China.
  • Yuan T; College of Life Science, Jiangxi Normal University Nanchang 330022, China.
Zhongguo Zhong Yao Za Zhi ; 46(18): 4744-4748, 2021 Sep.
Article em Zh | MEDLINE | ID: mdl-34581084
Four new lanostane triterpenoids, 3ß-hydroxy-12α-methoxylanosta-7,9(11),24-triene(1), 3ß-hydroxy-12α-methoxy-24-methylene-lanost-7,9(11)-dien(2), 3,7-dioxo-lanosta-8,24-diene(3), and 3,7-dioxo-24-methylene-lanost-8-en(4), were isolated from the latex of Euphorbia resinifera with a variety of chromatography methods. Their structures were elucidated based on spectroscopic data and/or comparison with the data reported in previous research. Compounds 1, 2, and 4 showed moderate inhibition of LPS-induced NO production by RAW264.7, with IC_(50) of 30.4, 37.5, and 28.3 µmol·L~(-1), respectively.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Euphorbia Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Euphorbia Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China