Nodular fasciitis of the breast: Report of two cases illustrating the diagnostic implications for USP6 gene rearrangement and brief review of the literature.
Exp Mol Pathol
; 123: 104690, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-34592198
ABSTRACT
Nodular fasciitis is a benign, self-limited, pseudosarcomatous neoplasm that is cytogenetically characterized by recurrent USP6 gene rearrangement. Involvement of the breast by nodular fasciitis is very rare with only a few documented cases. It can clinically, radiologically and histologically mimic a malignancy, posing significant diagnostic challenges to clinicians, radiologists, and pathologists. In this study, we report 2 cases of nodular fasciitis occurring in the female breast, reviewing the literature and emphasizing the application of fluorescence in situ hybridization analysis of USP6 gene rearrangement in its diagnosis and differential diagnosis.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mama
/
Ubiquitina Tiolesterase
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Fasciite
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Neoplasias
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
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Middle aged
Idioma:
En
Revista:
Exp Mol Pathol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China