The role of Sirtuin 2 in sustaining functional integrity of the liver.

Park, SunYoung; Chung, Myung-Jin; Son, Ji-Yoon; Yun, Hyun Ho; Park, Jae-Min; Yim, Jae-Hyuk; Jung, Seung-Jun; Lee, Sang-Han; Jeong, Kyu-Shik

Park, SunYoung; Chung, Myung-Jin; Son, Ji-Yoon; Yun, Hyun Ho; Park, Jae-Min; Yim, Jae-Hyuk; Jung, Seung-Jun; Lee, Sang-Han; Jeong, Kyu-Shik.

Afiliação

Park S; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea; Stem Cell Therapeutic Research Institute, Kyungpook National University, Daegu 41566, Republic of Korea.
Chung MJ; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Son JY; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Yun HH; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Park JM; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Yim JH; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Jung SJ; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Lee SH; Department of Food Science and Biotechnology, Graduate School, Kyungpook National University, Daegu 41566, Republic of Korea.
Jeong KS; Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea; Stem Cell Therapeutic Research Institute, Kyungpook National University, Daegu 41566, Republic of Korea. Electronic address: jeongks@knu.ac.kr.

Life Sci ; 285: 119997, 2021 Nov 15.

Article em En | MEDLINE | ID: mdl-34597608

Assuntos

Gorduras/metabolismo; Cirrose Hepática/metabolismo; Sirtuína 2/fisiologia; Animais; Senescência Celular; Dieta Hiperlipídica; Glicogênio/metabolismo; Homeostase; Gordura Intra-Abdominal/metabolismo; Fígado/citologia; Fígado/patologia; Cirrose Hepática/genética; Cirrose Hepática/patologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Sirtuína 2/genética; Aumento de Peso/genética

Palavras-chave

Cellular senescence; Fibrosis; High-fat diet; Lipid metabolism; NAFLD; SIRT2

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gorduras / Sirtuína 2 / Cirrose Hepática Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2021 Tipo de documento: Article

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