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The prevalence, predictors and outcomes of acute liver injury among patients with COVID-19: A systematic review and meta-analysis.
Harapan, Harapan; Fajar, Jonny Karunia; Supriono, Supriono; Soegiarto, Gatot; Wulandari, Laksmi; Seratin, Fiha; Prayudi, Nyoman Gede; Dewi, Dara Puspita; Monica Elsina, Maria Theresia; Atamou, Lasarus; Wiranata, Sinta; Aprianto, Dhito Pemi; Friska, Erlin; Sari Firdaus, D Fitria; Alaidin, Makdum; Wardhani, Firdha Aprillia; Husnah, Milda; Hidayati, Nurdina Wahyu; Hendriyanti, Yeni; Wardani, Kristia; Evatta, Arde; Manugan, Reizal Audi; Pradipto, Wiryawan; Rahmawati, Ade; Tamara, Fredo; Mahendra, Aditya Indra; Nainu, Firzan; Santoso, Budi; Irawan Primasatya, Chandra Adi; Tjionganata, Nindy; Budiman, Hendarto Arif.
Afiliação
  • Harapan H; Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
  • Fajar JK; Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
  • Supriono S; Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
  • Soegiarto G; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Wulandari L; Department of Internal Medicine, Division of Gastro-Entero-Hepatology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Seratin F; Department of Internal Medicine, Division of Allergy & Immunology, Universitas Airlangga, Surabaya, Indonesia.
  • Prayudi NG; Department of Pulmonology and Respiratory Medicine, Universitas Airlangga, Surabaya, Indonesia.
  • Dewi DP; Department of Paediatric, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia.
  • Monica Elsina MT; Department of Urology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Atamou L; Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
  • Wiranata S; Faculty of Nursing, Universitas Indonesia, Depok, Indonesia.
  • Aprianto DP; Faculty of Nursing, Universitas Indonesia, Depok, Indonesia.
  • Friska E; Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.
  • Sari Firdaus DF; Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
  • Alaidin M; Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.
  • Wardhani FA; Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.
  • Husnah M; Department of Nursing, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia.
  • Hidayati NW; Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
  • Hendriyanti Y; Master Program of Biology, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia.
  • Wardani K; Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
  • Evatta A; Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
  • Manugan RA; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Pradipto W; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Rahmawati A; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Tamara F; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Mahendra AI; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Nainu F; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Santoso B; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
  • Irawan Primasatya CA; Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia.
  • Tjionganata N; Department of Internal Medicine, RSUD Bangil, Pasuruan, Indonesia.
  • Budiman HA; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Rev Med Virol ; 32(3): e2304, 2022 05.
Article em En | MEDLINE | ID: mdl-34643006
The data on the predictors and prognosis of acute liver injury (ALI) among patients in coronavirus disease 2019 (COVID-19) patients are limited. The aim of this study was to determine the prevalence, predictors and outcomes of ALI among patients with COVID-19. A systematic review was conducted up to 10 June 2021. The relevant papers were searched from PubMed, Embase, Cochrane and Web of Science, and the data were analysed using a Z test. A total of 1331 papers were identified and 16 papers consisting of 1254 COVID-19 with ALI and 4999 COVID-19 without ALI were analysed. The cumulative prevalence of ALI among patients with COVID-19 was 22.8%. Male and having low lymphocyte levels were more likely to be associated with ALI compared with female and having higher lymphocyte level, odds ratio (OR): 2.70; 95% confidence interval (CI): 2.03, 3.60 and mean difference (MD) -125; 95% CI: -207, -43, respectively. COVID-19 patients with ALI had higher risk of developing severe COVID-19 compared with those without ALI (OR: 3.61; 95% CI: 2.60, 5.02). Our findings may serve as the additional evaluation for the management of ALI in COVID-19 patients.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Male Idioma: En Revista: Rev Med Virol Assunto da revista: VIROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Indonésia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Male Idioma: En Revista: Rev Med Virol Assunto da revista: VIROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Indonésia