Ganoderterpene A, a New Triterpenoid from <i>Ganoderma lucidum</i>, Attenuates LPS-Induced Inflammation and Apoptosis via Suppressing MAPK and TLR-4/NF-&#954;B Pathways in BV-2 Cells.

Kou, Rong-Wei; Gao, Yu-Qi; Xia, Bing; Wang, Jia-Yun; Liu, Xiao-Ning; Tang, Jiang-Jiang; Yin, Xia; Gao, Jin-Ming

Ganoderterpene A, a New Triterpenoid from Ganoderma lucidum, Attenuates LPS-Induced Inflammation and Apoptosis via Suppressing MAPK and TLR-4/NF-κB Pathways in BV-2 Cells.

Kou, Rong-Wei; Gao, Yu-Qi; Xia, Bing; Wang, Jia-Yun; Liu, Xiao-Ning; Tang, Jiang-Jiang; Yin, Xia; Gao, Jin-Ming.

Afiliação

Kou RW; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Gao YQ; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Xia B; College of Food Science and Engineering, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Wang JY; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Liu XN; College of Food Science and Engineering, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Tang JJ; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Yin X; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.
Gao JM; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, People's Republic of China.

J Agric Food Chem ; 69(43): 12730-12740, 2021 Nov 03.

Article em En | MEDLINE | ID: mdl-34666484

Assuntos

Ganoderma; Reishi; Triterpenos; Apoptose; Humanos; Inflamação/induzido quimicamente; Inflamação/tratamento farmacológico; Lipopolissacarídeos; Simulação de Acoplamento Molecular; NF-kappa B/genética; Receptor 4 Toll-Like/genética; Triterpenos/farmacologia

Palavras-chave

Ganoderma lucidum; anti-inflammatory; apoptosis; lanostane triterpenoid; mitochondrial dysfunction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Reishi / Ganoderma Limite: Humans Idioma: En Revista: J Agric Food Chem Ano de publicação: 2021 Tipo de documento: Article

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