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Exposure to inorganic particles in paediatric sarcoidosis: the PEDIASARC study.
Nathan, Nadia; Montagne, Marie-Emeline; Macchi, Odile; Rosental, Paul-André; Chauveau, Simon; Jeny, Florence; Sesé, Lucile; Abou Taam, Rola; Brocvielle, Manon; Brouard, Jacques; Catinon, Mickaël; Chapelon-Abric, Catherine; Cohen-Aubart, Fleur; Delacourt, Christophe; Delestrain, Céline; Deschildre, Antoine; Dossier, Antoine; Epaud, Ralph; Haroche, Julien; Houdouin, Véronique; Israel-Biet, Dominique; Juvin, Karine; Le Jeune, Sylvain; Lionnet, Francois; Meinzer, Ulrich; Mittaine, Marie; Nunes, Hilario; Mattioni, Sarah; Naccache, Jean-Marc; Odièvre, Marie-Hélène; Vincent, Michel; Clement, Annick; Valeyre, Dominique; Cavalin, Catherine.
Afiliação
  • Nathan N; Pediatric Pulmonology Department and Reference Center for Rare Lung Diseases RespiRare, Inserm UMR_S933 Laboratory of Childhood Genetic Diseases, Armand Trousseau Hospital, AP-HP. Sorbonne Université, Paris, France nadia.nathan@aphp.fr.
  • Montagne ME; Pediatric Pulmonology Department and Reference Center for Rare Lung Diseases RespiRare, Armand Trousseau Hospital, AP-HP. Sorbonne Université, Paris, France.
  • Macchi O; Observatoire, Samu Social de Paris, Paris, France.
  • Rosental PA; Centre d'Histoire, Sciences Po, Paris, France.
  • Chauveau S; Pulmonology Department and Inserm UMR 127, Avicenne Hospital, APHP. Université Sorbonne Paris Nord, Paris, France.
  • Jeny F; Pulmonology Department and Inserm UMR 127, Avicenne Hospital, APHP. Université Sorbonne Paris Nord, Paris, France.
  • Sesé L; Pulmonology Department and Inserm UMR 127, Avicenne Hospital, APHP. Université Sorbonne Paris Nord, Paris, France.
  • Abou Taam R; Pediatric Pulmonology Department and Reference Center for Rare Lung Diseases RespiRare, Necker Enfants Malades Hospital, AP-HP. Centre - Université de Paris, Paris, France.
  • Brocvielle M; Statistician, Marcq-en-Baroeul, France.
  • Brouard J; Pediatric Pulmonology Department, CHU Caen, Caen, France.
  • Catinon M; MINAPATH : SAS sociale et solidaire, Lyon, France.
  • Chapelon-Abric C; Department of Internal Medicine and Clinical Immunology, La Pitié-Salpêtrière Hospital, APHP. Sorbonne Université, Paris, France.
  • Cohen-Aubart F; Department of Internal Medicine 2, La Pitié-Salpêtrière Hospital, e3m Institute, Reference Center for Rare Systemic Diseases, Lupus, Anti-Phospholipids Syndrome, AP-HP. Sorbonne Université, Paris, France.
  • Delacourt C; Pediatric Pulmonology Department and Reference Center for Rare Lung Diseases RespiRare, Necker Enfants Malades Hospital, AP-HP. Centre - Université de Paris, Paris, France.
  • Delestrain C; Pediatric Department and Reference Center for Rare Lung Diseases RespiRare, INSERM, IMRB, Centre Hospitalier Intercommunal de Créteil, Université Paris Est Creteil, Paris, France.
  • Deschildre A; Pediatric pulmonology and allergy department, Hôpital Jeanne de Flandre, Université de Lille, Lille, France.
  • Dossier A; Department of Internal Medicine, Bichat Hospital, AP-HP. Nord - Université de Paris, Paris, France.
  • Epaud R; Centre Hospitalier Intercommunal de Créteil, Pediatric Department and Reference center for rare lung diseases (RespiRare), INSERM, IMRB, Université Paris Est Creteil, Paris, France.
  • Haroche J; Department of Internal Medicine 2, La Pitié-Salpêtrière Hospital, e3m Institute, Reference Center for Rare Systemic Diseases, Lupus, Anti-Phospholipids Syndrome, AP-HP. Sorbonne Université, Paris, France.
  • Houdouin V; Pediatric Pulmonology department, Robert Debré Hospital, AP-HP. Nord - Université de Paris, Paris, France.
  • Israel-Biet D; Pulmonology department, Georges Pompidou Hospital, AP-HP. Centre - Université de Paris, Paris, France.
  • Juvin K; Pulmonology department, Georges Pompidou Hospital, AP-HP. Centre - Université de Paris, Paris, France.
  • Le Jeune S; Department of Internal Medicine, Avicenne Hospital, APHP. Université Sorbonne Paris Nord, Paris, France.
  • Lionnet F; Department of Internal Medicine, Tenon Hospital, AP-HP. Sorbonne Université, Paris, France.
  • Meinzer U; Department of General Pediatrics, Pediatric Internal Medicine, Rheumatology and Infectious Diseases, National Referee Center for Rare Pediatric Inflammatory Rheumatisms and Systemic Auto-Immune Diseases RAISE, Robert Debré Hospital, AP-HP. Nord - Université de Paris, Paris, France.
  • Mittaine M; Pediatric Pulmonology Department, Children Hospital, CHU Toulouse, Toulouse, France.
  • Nunes H; Pulmonology Department and Inserm UMR 127, Avicenne Hospital, APHP. Université Sorbonne Paris Nord, Paris, France.
  • Mattioni S; Department of Internal Medicine, Tenon Hospital, AP-HP. Sorbonne Université, Paris, France.
  • Naccache JM; Pulmonology Department, Groupe hospitalier Paris Saint-Joseph and Hôpital Foch, Paris, France.
  • Odièvre MH; Department of Pediatrics and Sickle Cell Disease Center, Armand Trousseau Hospital, AP-HP. Sorbonne Université, Paris, France.
  • Vincent M; MINAPATH : SAS sociale et solidaire, Lyon, France.
  • Clement A; Pediatric Pulmonology Department and Reference Center for Rare Lung Diseases RespiRare, Inserm UMR_S933 Laboratory of Childhood Genetic Diseases, Armand Trousseau Hospital, AP-HP. Sorbonne Université, Paris, France.
  • Valeyre D; Pulmonology Department and Inserm UMR 127, Avicenne Hospital, APHP. Université Sorbonne Paris Nord, Paris, France.
  • Cavalin C; Pulmonology department, Paris Saint Joseph Hospital Group, Paris, France.
Thorax ; 77(4): 404-407, 2022 04.
Article em En | MEDLINE | ID: mdl-34675126
ABSTRACT
Inorganic antigens may contribute to paediatric sarcoidosis. Thirty-six patients matched with 36 healthy controls as well as a group of 21 sickle-cell disease (SCD) controls answered an environmental questionnaire. Patients' indirect exposure to inorganic particles, through coresidents' occupations, was higher than in healthy and SCD controls (median score 2.5 (0.5-7) vs 0.5 (0-2), p=0.003 and 1 (0-2), p=0.012, respectively), especially for construction, exposures to metal dust, talc, abrasive reagents and scouring products. Wood or fossil energies heating were also linked to paediatric sarcoidosis. This study supports a link between mineral environmental exposure due to adult coresident occupations and paediatric sarcoidosis.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoidose / Exposição Ocupacional Limite: Adult / Child / Humans Idioma: En Revista: Thorax Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoidose / Exposição Ocupacional Limite: Adult / Child / Humans Idioma: En Revista: Thorax Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França