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COVID-19 in children. II: Pathogenesis, disease spectrum and management.
Howard-Jones, Annaleise R; Burgner, David P; Crawford, Nigel W; Goeman, Emma; Gray, Paul E; Hsu, Peter; Kuek, Stephanie; McMullan, Brendan J; Tosif, Shidan; Wurzel, Danielle; Bowen, Asha C; Danchin, Margie; Koirala, Archana; Sharma, Ketaki; Yeoh, Daniel K; Britton, Philip N.
Afiliação
  • Howard-Jones AR; Discipline of Child and Adolescent Health, University of Sydney, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
  • Burgner DP; NSW Health Pathology-Nepean, Nepean Hospital, Sydney, New South Wales, Australia.
  • Crawford NW; Infectious Diseases Unit, Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia.
  • Goeman E; Infection and Immunity Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
  • Gray PE; Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.
  • Hsu P; Infection and Immunity Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
  • Kuek S; Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.
  • McMullan BJ; Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia.
  • Tosif S; Department of Infectious Diseases and Microbiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
  • Wurzel D; Department of Immunology and Infectious Diseases, Sydney Children's Hospital, Sydney, New South Wales, Australia.
  • Bowen AC; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Danchin M; Discipline of Child and Adolescent Health, University of Sydney, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
  • Koirala A; Department of Immunology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
  • Sharma K; Department of Respiratory and Sleep Medicine, The Royal Children's Hospital, Melbourne, Victoria, Australia.
  • Yeoh DK; Department of Immunology and Infectious Diseases, Sydney Children's Hospital, Sydney, New South Wales, Australia.
  • Britton PN; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.
J Paediatr Child Health ; 58(1): 46-53, 2022 Jan.
Article em En | MEDLINE | ID: mdl-34694037
ABSTRACT
The global disruption of the COVID-19 pandemic has impacted the life of every child either directly or indirectly. This review explores the pathophysiology, immune response, clinical presentation and treatment of COVID-19 in children, summarising the most up-to-date data including recent developments regarding variants of concern. The acute infection with SARS-CoV-2 is generally mild in children, whilst the post-infectious manifestations, including paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) and 'long COVID' in children, are more complex. Given that most research on COVID-19 has focused on adult cohorts and that clinical manifestations, treatment availability and impacts differ markedly in children, research that specifically examines COVID-19 in children needs to be prioritised.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Etiology_studies Limite: Child / Humans Idioma: En Revista: J Paediatr Child Health Assunto da revista: PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Etiology_studies Limite: Child / Humans Idioma: En Revista: J Paediatr Child Health Assunto da revista: PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália