A Clinical Trial Evaluating the Usefulness of Tailored Antimicrobial Prophylaxis Using Rectal-culture Screening Media Prior to Transrectal Prostate Biopsy: A Multicenter, Randomized Controlled Trial.
Acta Med Okayama
; 75(5): 663-667, 2021.
Article
em En
| MEDLINE
| ID: mdl-34703052
ABSTRACT
The aim of this report is to introduce an on-going, multicenter, randomized controlled trial to evaluate whether tailored antimicrobial prophylaxis guided by rectal culture screening prevents acute bacterial prostatitis following transrectal prostate biopsy (TRPB). Patients will be randomized into an intervention or non-intervention group; tazobactam-piperacillin or levofloxacin will be prophylactically administered according to the results of rectal culture prior to TRPB in the intervention group whereas levofloxacin will be routinely given in the non-intervention group. The primary endpoint is the occurrence rate of acute bacterial prostatitis after TRPB. Recruitment begins in April, 2021 and the target total sample size is 5,100 participants.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Prostáticas
/
Infecções Bacterianas
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Ensaios Clínicos Controlados Aleatórios como Assunto
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Estudos Multicêntricos como Assunto
/
Antibacterianos
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Screening_studies
Limite:
Humans
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Male
Idioma:
En
Revista:
Acta Med Okayama
Ano de publicação:
2021
Tipo de documento:
Article