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Patient-derived organoids as a platform for modeling a patient's response to chemoradiotherapy in esophageal cancer.
Karakasheva, Tatiana A; Gabre, Joel T; Sachdeva, Uma M; Cruz-Acuña, Ricardo; Lin, Eric W; DeMarshall, Maureen; Falk, Gary W; Ginsberg, Gregory G; Yang, Zhaohai; Kim, Michele M; Diffenderfer, Eric S; Pitarresi, Jason R; Li, Jinyang; Muir, Amanda B; Hamilton, Kathryn E; Nakagawa, Hiroshi; Bass, Adam J; Rustgi, Anil K.
Afiliação
  • Karakasheva TA; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Gabre JT; Gastrointestinal Epithelium Modeling Program, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Sachdeva UM; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Cruz-Acuña R; Division of Digestive and Liver Diseases, Department of Medicine and Herbert Irving Comprehensive Cancer Research Center, Columbia University Irving Medical Center, 1130 St. Nicholas Avenue, Suite 201, New York, NY, 10032, USA.
  • Lin EW; Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
  • DeMarshall M; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Falk GW; Herbert Irving Comprehensive Cancer Research Center, Columbia University Irving Medical Center, New York, NY, USA.
  • Ginsberg GG; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Yang Z; Massachusetts General Hospital, Boston, MA, USA.
  • Kim MM; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Diffenderfer ES; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Pitarresi JR; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Li J; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Muir AB; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Hamilton KE; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Nakagawa H; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Bass AJ; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Rustgi AK; Gastrointestinal Epithelium Modeling Program, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Sci Rep ; 11(1): 21304, 2021 10 29.
Article em En | MEDLINE | ID: mdl-34716381

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Organoides / Terapia Neoadjuvante / Quimiorradioterapia / Antineoplásicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Organoides / Terapia Neoadjuvante / Quimiorradioterapia / Antineoplásicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos