To grow and to stay, both controlled by RhoA: Opposing cellular effects on axon regeneration.

Hintermayer, Matthew A; Drake, Sienna S; Fournier, Alyson E

Hintermayer, Matthew A; Drake, Sienna S; Fournier, Alyson E.

Afiliação

Hintermayer MA; McGill University, Montréal Neurological Institute, Montréal, QC H3A 2B4, Canada.
Drake SS; McGill University, Montréal Neurological Institute, Montréal, QC H3A 2B4, Canada.
Fournier AE; McGill University, Montréal Neurological Institute, Montréal, QC H3A 2B4, Canada. Electronic address: alyson.fournier@mcgill.ca.

Neuron ; 109(21): 3395-3397, 2021 11 03.

Article em En | MEDLINE | ID: mdl-34735789

ABSTRACT

ABSTRACT

In this issue of Neuron, Stern et al. (2021) demonstrate that cell-type-specific ablation of RhoA differentially affects axon regeneration outcomes in spinal cord injury models. Their findings highlight the importance of considering cell-type-specific strategies to promote axon regeneration.

Assuntos

Axônios; Traumatismos da Medula Espinal; Humanos; Regeneração Nervosa; Neurônios; Traumatismos da Medula Espinal/terapia; Proteína rhoA de Ligação ao GTP

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal / Axônios Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá

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