Revealing the Relevant Spatiotemporal Scale Underlying Whole-Brain Dynamics.
Front Neurosci
; 15: 715861, 2021.
Article
em En
| MEDLINE
| ID: mdl-34744605
ABSTRACT
The brain rapidly processes and adapts to new information by dynamically transitioning between whole-brain functional networks. In this whole-brain modeling study we investigate the relevance of spatiotemporal scale in whole-brain functional networks. This is achieved through estimating brain parcellations at different spatial scales (100-900 regions) and time series at different temporal scales (from milliseconds to seconds) generated by a whole-brain model fitted to fMRI data. We quantify the richness of the dynamic repertoire at each spatiotemporal scale by computing the entropy of transitions between whole-brain functional networks. The results show that the optimal relevant spatial scale is around 300 regions and a temporal scale of around 150 ms. Overall, this study provides much needed evidence for the relevant spatiotemporal scales and recommendations for analyses of brain dynamics.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Front Neurosci
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Alemanha