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The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility.
Spliid, Charlotte B; Toledo, Alejandro Gomez; Sanderson, Patience; Mao, Yang; Gatto, Francesco; Gustavsson, Tobias; Choudhary, Swati; Saldanha, Ana L; Vogelsang, Rasmus P; Gögenur, Ismail; Theander, Thor G; Leach, Franklin E; Amster, I Jonathan; Esko, Jeffrey D; Salanti, Ali; Clausen, Thomas Mandel.
Afiliação
  • Spliid CB; Department of Cellular and Molecular Medicine, and Glycobiology Research and Training Center, University of California San Diego, La Jolla, California, USA; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen
  • Toledo AG; Department of Cellular and Molecular Medicine, and Glycobiology Research and Training Center, University of California San Diego, La Jolla, California, USA; Department of Clinical Sciences, Division of Infection Medicine, Lund University, Lund, Sweden.
  • Sanderson P; Department of Chemistry, University of Georgia, Athens, Georgia, USA.
  • Mao Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China and Guangdong Provincial Key Laboratory of Drug Non-Clinical Evaluation and Research, Guangzhou, China.
  • Gatto F; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
  • Gustavsson T; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, Copenhagen, Denmark.
  • Choudhary S; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, Copenhagen, Denmark.
  • Saldanha AL; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, Copenhagen, Denmark.
  • Vogelsang RP; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Koege, Denmark.
  • Gögenur I; Center for Surgical Science, Department of Surgery, Zealand University Hospital, Koege, Denmark.
  • Theander TG; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, Copenhagen, Denmark.
  • Leach FE; Department of Environmental Health Science, University of Georgia, Athens, Georgia, USA.
  • Amster IJ; Department of Chemistry, University of Georgia, Athens, Georgia, USA.
  • Esko JD; Department of Cellular and Molecular Medicine, and Glycobiology Research and Training Center, University of California San Diego, La Jolla, California, USA.
  • Salanti A; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, Copenhagen, Denmark.
  • Clausen TM; Department of Cellular and Molecular Medicine, and Glycobiology Research and Training Center, University of California San Diego, La Jolla, California, USA; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen
J Biol Chem ; 297(6): 101391, 2021 12.
Article em En | MEDLINE | ID: mdl-34762909
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Proteínas de Protozoários / Sulfatos de Condroitina / Malária Falciparum / Glicocálix / Antígenos de Protozoários Limite: Female / Humans / Pregnancy Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Proteínas de Protozoários / Sulfatos de Condroitina / Malária Falciparum / Glicocálix / Antígenos de Protozoários Limite: Female / Humans / Pregnancy Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article