Cysteine Restriction in Murine L929 Fibroblasts as an Alternative Strategy to Methionine Restriction in Cancer Therapy.

Schmitz, Werner; Ries, Elena; Koderer, Corinna; Völter, Maximilian Friedrich; Wünsch, Anna Chiara; El-Mesery, Mohamed; Frackmann, Kyra; Kübler, Alexander Christian; Linz, Christian; Seher, Axel

Schmitz, Werner; Ries, Elena; Koderer, Corinna; Völter, Maximilian Friedrich; Wünsch, Anna Chiara; El-Mesery, Mohamed; Frackmann, Kyra; Kübler, Alexander Christian; Linz, Christian; Seher, Axel.

Afiliação

Schmitz W; Department of Biochemistry and Molecular Biology, Biocenter, D-97074 Wuerzburg, Germany.
Ries E; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
Koderer C; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
Völter MF; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
Wünsch AC; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
El-Mesery M; Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Frackmann K; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
Kübler AC; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
Linz C; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.
Seher A; Department of Oral and Maxillofacial Plastic Surgery, University Hospital Wuerzburg, D-97070 Wuerzburg, Germany.

Int J Mol Sci ; 22(21)2021 Oct 27.

Article em En | MEDLINE | ID: mdl-34769059

Assuntos

Cisteína/metabolismo; Fibroblastos/metabolismo; Metionina/metabolismo; Neoplasias/metabolismo; Animais; Restrição Calórica/métodos; Linhagem Celular; Dieta/métodos; Camundongos

Palavras-chave

LC/MS; amino acid analogues; caloric restriction; cancer therapy; cysteine restriction; cysteine synthase inhibitor; homocysteine; mass spectrometry; methionine restriction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Fibroblastos / Metionina / Neoplasias Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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