Awakening sleeper cells: a narrative review on bacterial magic spot synthetases as potential drug targets to overcome persistence.

Veetilvalappil, Vimal Venu; Aranjani, Jesil Mathew; Mahammad, Fayaz Shaik; Joseph, Alex

Veetilvalappil, Vimal Venu; Aranjani, Jesil Mathew; Mahammad, Fayaz Shaik; Joseph, Alex.

Afiliação

Veetilvalappil VV; Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Udupi, Karnataka, 576104, India.
Aranjani JM; Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Udupi, Karnataka, 576104, India. jesilmathew@gmail.com.
Mahammad FS; Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Udupi, Karnataka, 576104, India.
Joseph A; Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Udupi, Karnataka, 576104, India.

Curr Genet ; 68(1): 49-60, 2022 Feb.

Article em En | MEDLINE | ID: mdl-34787710

Assuntos

Proteínas de Bactérias; Ligases; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Bactérias/genética; Bactérias/metabolismo; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Guanosina Pentafosfato/metabolismo; Ligases/genética; Virulência/genética

Palavras-chave

Alarmone synthesis; Bacterial magic spots; Bacterial stress survival mechanism; Rel/SpoT homologs; Stringent response; Wake persister cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Ligases Idioma: En Revista: Curr Genet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

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