A novel method development and validation for determination of 2,4,6-Trinitrotoluene and its metabolites on LC-MS/MS.

Aamir, Muhammad; Irum, Sobia; Siddiq, Amer; Batool, Hafiza Monaza; Ahmed, Nisar; Awais, Muhammad Hamid; Ali, Sadiq

Aamir, Muhammad; Irum, Sobia; Siddiq, Amer; Batool, Hafiza Monaza; Ahmed, Nisar; Awais, Muhammad Hamid; Ali, Sadiq.

Afiliação

Aamir M; Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan. Electronic address: ashmir83@yahoo.com.
Irum S; Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan. Electronic address: Sobiairum2711@hotmail.com.
Siddiq A; Watim Medical & Dental College, Rawalpindi, Pakistan. Electronic address: amersiddiq@yahoo.com.
Batool HM; Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan; Forensic Toxicology Department, Armed Forces Institute of Pathology, Rawalpindi, Pakistan. Electronic address: monazabatool786@gmail.com.
Ahmed N; Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan; Forensic Toxicology Department, Armed Forces Institute of Pathology, Rawalpindi, Pakistan. Electronic address: nisarafip@gmail.com.
Awais MH; Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan. Electronic address: awaismangat@gmail.com.
Ali S; Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan; Forensic Toxicology Department, Armed Forces Institute of Pathology, Rawalpindi, Pakistan. Electronic address: sadiq.forensic.toxi@gmail.com.

Anal Biochem ; 638: 114496, 2022 02 01.

Article em En | MEDLINE | ID: mdl-34838816

Assuntos

Cromatografia Líquida/métodos; Espectrometria de Massas em Tandem/métodos; Trinitrotolueno/urina; Desenho de Equipamento; Humanos; Trinitrotolueno/metabolismo

Palavras-chave

Liquid chromatography-mass spectrometry mass spectrometry (LC/MS/MS); Lower limit of quantitation (LLOQ); Method development; Trinitrotoluene (TNT); Validation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trinitrotolueno / Cromatografia Líquida / Espectrometria de Massas em Tandem Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Anal Biochem Ano de publicação: 2022 Tipo de documento: Article

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