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Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling.
Smith, Roger S; Odintsov, Igor; Liu, Zebing; Lui, Allan Jo-Weng; Hayashi, Takuo; Vojnic, Morana; Suehara, Yoshiyuki; Delasos, Lukas; Mattar, Marissa S; Hmeljak, Julija; Ramirez, Hillary A; Shaw, Melissa; Bui, Gabrielle; Hartono, Alifiani B; Gladstone, Eric; Kunte, Siddharth; Magnan, Heather; Khodos, Inna; De Stanchina, Elisa; La Quaglia, Michael P; Yao, Jinjuan; Laé, Marick; Lee, Sean B; Spraggon, Lee; Pratilas, Christine A; Ladanyi, Marc; Somwar, Romel.
Afiliação
  • Smith RS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Odintsov I; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Liu Z; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Lui AJ; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Hayashi T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Vojnic M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Suehara Y; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Delasos L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Mattar MS; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Hmeljak J; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Ramirez HA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Shaw M; Anti-tumor Assessment Core Facility, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Bui G; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Hartono AB; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Gladstone E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Kunte S; Gerstner School of Graduate Studies, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Magnan H; Gerstner School of Graduate Studies, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Khodos I; Tulane University School of Medicine, New Orleans, LA 70118, USA.
  • De Stanchina E; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • La Quaglia MP; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Yao J; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Laé M; Anti-tumor Assessment Core Facility, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Lee SB; Anti-tumor Assessment Core Facility, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Spraggon L; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Pratilas CA; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Somwar R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Dis Model Mech ; 15(1)2022 01 01.
Article em En | MEDLINE | ID: mdl-34841430

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tumor Desmoplásico de Pequenas Células Redondas Limite: Animals / Humans Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tumor Desmoplásico de Pequenas Células Redondas Limite: Animals / Humans Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos