Perillyl Alcohol Attenuates NLRP3 Inflammasome Activation and Rescues Dopaminergic Neurons in Experimental In Vitro and In Vivo Models of Parkinson's Disease.

Ahmed, Sahabuddin; Panda, Samir Ranjan; Kwatra, Mohit; Sahu, Bidya Dhar; Naidu, Vgm

Ahmed, Sahabuddin; Panda, Samir Ranjan; Kwatra, Mohit; Sahu, Bidya Dhar; Naidu, Vgm.

Afiliação

Ahmed S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Changsari, Kamrup, Assam 781101, India.
Panda SR; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Changsari, Kamrup, Assam 781101, India.
Kwatra M; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Changsari, Kamrup, Assam 781101, India.
Sahu BD; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Changsari, Kamrup, Assam 781101, India.
Naidu V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Changsari, Kamrup, Assam 781101, India.

ACS Chem Neurosci ; 13(1): 53-68, 2022 01 05.

Article em En | MEDLINE | ID: mdl-34904823

Assuntos

Inflamassomos; Doença de Parkinson; Animais; Neurônios Dopaminérgicos; Peróxido de Hidrogênio; Camundongos; Monoterpenos; Proteína 3 que Contém Domínio de Pirina da Família NLR

Palavras-chave

NF-κB; NLRP3 inflammasome; Parkinson's disease; microglial activation; mitochondrial dysfunction; perillyl alcohol; reactive oxygen species

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Inflamassomos Limite: Animals Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

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