Ameliorative effect of flavonoid-rich extracts from <i>Gongronema latifolium</i> against diabetic cardiomyopathy via serpin A<sub>3</sub> and socs3-a in streptozocin treated rats.

Oyinloye, Babatunji Emmanuel; Ajiboye, Basiru Olaitan; Johnson, Oluwafolakemi; Owolabi, Olutunmise Victoria; Ejeje, Jerius Nkwuda; Brai, Bartholomew I C; Omotuyi, Olaposi Idowu

Ameliorative effect of flavonoid-rich extracts from Gongronema latifolium against diabetic cardiomyopathy via serpin A₃ and socs3-a in streptozocin treated rats.

Oyinloye, Babatunji Emmanuel; Ajiboye, Basiru Olaitan; Johnson, Oluwafolakemi; Owolabi, Olutunmise Victoria; Ejeje, Jerius Nkwuda; Brai, Bartholomew I C; Omotuyi, Olaposi Idowu.

Afiliação

Oyinloye BE; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Ajiboye BO; Institute of Drug Research and Development, SE Bogoro Center, Afe Babalola University, Ado-Ekiti, Nigeria.
Johnson O; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, South Africa.
Owolabi OV; Institute of Drug Research and Development, SE Bogoro Center, Afe Babalola University, Ado-Ekiti, Nigeria.
Ejeje JN; Phytomedicine and Molecular Toxicology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti, Nigeria.
Brai BIC; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Omotuyi OI; Medical Biochemistry Unit, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.

Biomarkers ; 27(2): 169-177, 2022 Mar.

Article em En | MEDLINE | ID: mdl-34951557

Assuntos

Apocynaceae; Diabetes Mellitus Experimental; Cardiomiopatias Diabéticas; Serpinas; Animais; Apocynaceae/metabolismo; Glicemia/metabolismo; Diabetes Mellitus Experimental/tratamento farmacológico; Diabetes Mellitus Experimental/metabolismo; Cardiomiopatias Diabéticas/tratamento farmacológico; Flavonoides/farmacologia; Flavonoides/uso terapêutico; Humanos; Hipoglicemiantes/farmacologia; Hipoglicemiantes/uso terapêutico; Extratos Vegetais/farmacologia; Ratos; Ratos Wistar; Estreptozocina/efeitos adversos; Proteína 3 Supressora da Sinalização de Citocinas

Palavras-chave

Isolate; antioxidant enzymes; flavonoid; gene expression; histology; lipid profiles

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serpinas / Apocynaceae / Diabetes Mellitus Experimental / Cardiomiopatias Diabéticas Limite: Animals / Humans Idioma: En Revista: Biomarkers Assunto da revista: BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Nigéria

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google