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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome.
Jewell, Brittany E; Xu, An; Zhu, Dandan; Huang, Mo-Fan; Lu, Linchao; Liu, Mo; Underwood, Erica L; Park, Jun Hyoung; Fan, Huihui; Gingold, Julian A; Zhou, Ruoji; Tu, Jian; Huo, Zijun; Liu, Ying; Jin, Weidong; Chen, Yi-Hung; Xu, Yitian; Chen, Shu-Hsia; Rainusso, Nino; Berg, Nathaniel K; Bazer, Danielle A; Vellano, Christopher; Jones, Philip; Eltzschig, Holger K; Zhao, Zhongming; Kaipparettu, Benny Abraham; Zhao, Ruiying; Wang, Lisa L; Lee, Dung-Fang.
Afiliação
  • Jewell BE; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Xu A; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, United States of America.
  • Zhu D; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Huang MF; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Lu L; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Liu M; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, United States of America.
  • Underwood EL; Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, United States of America.
  • Park JH; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Fan H; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Gingold JA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
  • Zhou R; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Tu J; Department of Obstetrics & Gynecology and Women's Health, Einstein/Montefiore Medical Center, New York City, New York, United States of America.
  • Huo Z; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Liu Y; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Jin W; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Chen YH; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Xu Y; Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, United States of America.
  • Chen SH; Department and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Rainusso N; Center for Immunotherapy Research, Cancer Center of Excellence, Houston Methodist Research Institute, Houston, Texas, United States of America.
  • Berg NK; Center for Immunotherapy Research, Cancer Center of Excellence, Houston Methodist Research Institute, Houston, Texas, United States of America.
  • Bazer DA; Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, United States of America.
  • Vellano C; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, United States of America.
  • Jones P; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Eltzschig HK; Department of Neurology, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York, United States of America.
  • Zhao Z; TRACTION Platform, Therapeutics Discovery Division, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
  • Kaipparettu BA; TRACTION Platform, Therapeutics Discovery Division, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
  • Zhao R; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, United States of America.
  • Wang LL; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
  • Lee DF; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, United States of America.
PLoS Genet ; 17(12): e1009971, 2021 12.
Article em En | MEDLINE | ID: mdl-34965247
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Rothmund-Thomson / Osteossarcoma / Complexo I de Transporte de Elétrons / RecQ Helicases / RNA Longo não Codificante Limite: Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Rothmund-Thomson / Osteossarcoma / Complexo I de Transporte de Elétrons / RecQ Helicases / RNA Longo não Codificante Limite: Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos