Protective effect of Yangxue Jiedu Soup against psoriasis-like lesions by regulating TLR4/NF-&#954;B signaling pathway mediated by secretion of exosome HSP70.

Lv, Jingjing; Wang, Yan; Xu, Jingna; Zhou, Tao; Chen, Zhaoxia; Yang, Haoyu; Di, Tingting; Li, Ping

Protective effect of Yangxue Jiedu Soup against psoriasis-like lesions by regulating TLR4/NF-κB signaling pathway mediated by secretion of exosome HSP70.

Lv, Jingjing; Wang, Yan; Xu, Jingna; Zhou, Tao; Chen, Zhaoxia; Yang, Haoyu; Di, Tingting; Li, Ping.

Afiliação

Lv J; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Wang Y; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China; Beijing Institute of Chinese Medicine, Beijing 100010, China.
Xu J; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Zhou T; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Chen Z; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China; Beijing Institute of Chinese Medicine, Beijing 100010, China.
Yang H; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Di T; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
Li P; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China; Beijing Institute of Chinese Medicine, Beijing 100010, China. Electronic address: liping@bjzhongyi.com.

Biomed Pharmacother ; 147: 112604, 2022 Mar.

Article em En | MEDLINE | ID: mdl-34998030

Assuntos

Anti-Inflamatórios/farmacologia; Medicamentos de Ervas Chinesas/farmacologia; Psoríase/prevenção & controle; Animais; Anti-Inflamatórios/química; Anti-Inflamatórios/uso terapêutico; Modelos Animais de Doenças; Medicamentos de Ervas Chinesas/química; Medicamentos de Ervas Chinesas/uso terapêutico; Proteínas de Choque Térmico HSP70/metabolismo; Imiquimode; Masculino; Camundongos; Camundongos Endogâmicos BALB C; NF-kappa B/metabolismo; Fitoterapia; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/metabolismo

Palavras-chave

Exosome HSP70; Imiquimod; Psoriasis-like lesions; TLR4/NF-κB signaling pathway; Yangxue Jiedu Soup

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Medicamentos de Ervas Chinesas / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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