Your browser doesn't support javascript.
loading
Glycemic response, satiety, gastric secretions and emptying after bread consumption with water, tea or lemon juice: a randomized crossover intervention using MRI.
Freitas, Daniela; Boué, François; Benallaoua, Mourad; Airinei, Gheorghe; Benamouzig, Robert; Lutton, Evelyne; Jourdain, Laurène; Dubuisson, Rose-Marie; Maître, Xavier; Darrasse, Luc; Le Feunteun, Steven.
Afiliação
  • Freitas D; Université Paris-Saclay, INRAE, AgroParisTech, UMR SayFood, 78850, Thiverval-Grignon, France.
  • Boué F; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland.
  • Benallaoua M; CEFRED (Centre d'exploration Fonctionnelle et de Rééducation Digestive), Hôpital Avicenne, Service de gastro-entérologie, Bobigny Cedex, France.
  • Airinei G; Laboratoire Léon Brillouin UMR 12, CNRS - CEA Université Paris-Saclay, 91191, Gif-sur-Yvette Cedex, France.
  • Benamouzig R; CEFRED (Centre d'exploration Fonctionnelle et de Rééducation Digestive), Hôpital Avicenne, Service de gastro-entérologie, Bobigny Cedex, France.
  • Lutton E; CEFRED (Centre d'exploration Fonctionnelle et de Rééducation Digestive), Hôpital Avicenne, Service de gastro-entérologie, Bobigny Cedex, France.
  • Jourdain L; CEFRED (Centre d'exploration Fonctionnelle et de Rééducation Digestive), Hôpital Avicenne, Service de gastro-entérologie, Bobigny Cedex, France.
  • Dubuisson RM; Université Paris-Saclay, INRAE, AgroParisTech, UMR SayFood, 78850, Thiverval-Grignon, France.
  • Maître X; MIA, INRAE, ISC-PIF, 75013, Paris, France.
  • Darrasse L; Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Orsay, France.
  • Le Feunteun S; Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Orsay, France.
Eur J Nutr ; 61(3): 1621-1636, 2022 Apr.
Article em En | MEDLINE | ID: mdl-35013789
ABSTRACT

PURPOSE:

Numerous studies, including our previous work with lemon juice, have reported that low-pH meals reduce the glycemic response to starchy foods. However, the underlying mechanism is not yet understood. Tea, for its polyphenol content, has also been investigated. The main objective of this research was to concurrently study gastric emptying, appetite perceptions and glycemic responses to bread consumed with water, tea, or lemon juice.

METHODS:

In this randomized, crossover intervention, ten participants consumed equal portions of bread (100 g) with 250 mL of water, water-diluted lemon juice, or black tea at breakfast. Gastric volumes, blood glucose concentrations and appetite perceptions were alternately assessed over 180 min using magnetic resonance imaging, the finger-prick method and visual analogue scales, respectively.

RESULTS:

Compared to water, lemon juice led to a 1.5 fold increase of the volume of gastric contents, 30 min after the meal (454.0 ± 18.6 vs. 298.4 ± 19.5 mL, [Formula see text] ± SEM P < 0.00001). Gastric emptying was also 1.5 times faster (P < 0.01). Conversely, lemon juice elicited a lower glycemic response than water (blood glucose concentrations at t = 55 min were 35% lower, P = 0.039). Tea had no effect. Changes in appetite perceptions and gastric volumes correlated well, but with no significant differences between the meals.

CONCLUSIONS:

Lemon juice lowered the glycemic response and increased both gastric secretions and emptying rate. The results are compatible with the hypothesis that the reduction of the glycemic response is mainly due to the interruption of starch hydrolysis via the acid-inhibition of salivary α-amylase. TRIAL REGISTRATION NUMBER NCT03265392, August 29, 2017.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Pão Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Eur J Nutr Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Pão Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Eur J Nutr Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França