Alterations in the kynurenine pathway and excitatory amino acid transporter-2 in depression with and without psychosis: Evidence of a potential astrocyte pathology.

Brown, Samara J; Brown, Amelia M; Purves-Tyson, Tertia D; Huang, Xu-Feng; Shannon Weickert, Cynthia; Newell, Kelly A

Brown, Samara J; Brown, Amelia M; Purves-Tyson, Tertia D; Huang, Xu-Feng; Shannon Weickert, Cynthia; Newell, Kelly A.

Afiliação

Brown SJ; School of Medicine and Molecular Horizons, University of Wollongong, Wollongong, NSW, 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, New South Wales, 2522, Australia.
Brown AM; Schizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia.
Purves-Tyson TD; Schizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia; School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, New South Wales, 2031, Australia.
Huang XF; School of Medicine and Molecular Horizons, University of Wollongong, Wollongong, NSW, 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, New South Wales, 2522, Australia.
Shannon Weickert C; Schizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia; School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, New South Wales, 2031, Australia; Department of Neuroscience & Physiology, Upstate Medical Universit
Newell KA; School of Medicine and Molecular Horizons, University of Wollongong, Wollongong, NSW, 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, New South Wales, 2522, Australia. Electronic address: knewell@uow.edu.au.

J Psychiatr Res ; 147: 203-211, 2022 03.

Article em En | MEDLINE | ID: mdl-35063739

Assuntos

Transtorno Depressivo Maior; Transtornos Psicóticos; Astrócitos/metabolismo; Depressão; Transtorno Depressivo Maior/metabolismo; Humanos; Ácido Cinurênico/metabolismo; Cinurenina

Palavras-chave

Astrocyte; Depression; Excitatory amino acid transporter 2 (EAAT2); Glutamate; Kynurenine aminotransferase; Kynurenine pathway

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Transtorno Depressivo Maior Limite: Humans Idioma: En Revista: J Psychiatr Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália

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